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NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis.
Nature. 2017 Nov 30;551(7682):639-643. doi: 10.1038/nature24637. Epub 2017 Nov 22.
Nature. 2017.
PMID: 29168506
Free PMC article.
Author Correction: NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis.
Alvarez SW, Sviderskiy VO, Terzi EM, Papagiannakopoulos T, Moreira AL, Adams S, Sabatini DM, Birsoy K, Possemato R.
Alvarez SW, et al.
Nature. 2022 Sep;609(7929):E12. doi: 10.1038/s41586-022-05323-7.
Nature. 2022.
PMID: 36104569
No abstract available.
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Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer.
Sayin VI, LeBoeuf SE, Singh SX, Davidson SM, Biancur D, Guzelhan BS, Alvarez SW, Wu WL, Karakousi TR, Zavitsanou AM, Ubriaco J, Muir A, Karagiannis D, Morris PJ, Thomas CJ, Possemato R, Vander Heiden MG, Papagiannakopoulos T.
Sayin VI, et al. Among authors: alvarez sw.
Elife. 2017 Oct 2;6:e28083. doi: 10.7554/eLife.28083.
Elife. 2017.
PMID: 28967864
Free PMC article.
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Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs.
Minton DR, Nam M, McLaughlin DJ, Shin J, Bayraktar EC, Alvarez SW, Sviderskiy VO, Papagiannakopoulos T, Sabatini DM, Birsoy K, Possemato R.
Minton DR, et al. Among authors: alvarez sw.
Mol Cell. 2018 Feb 15;69(4):610-621.e5. doi: 10.1016/j.molcel.2018.01.024.
Mol Cell. 2018.
PMID: 29452640
Free PMC article.
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Leveraging the iron-starvation response to promote ferroptosis.
Alvarez SW, Possemato R.
Alvarez SW, et al.
Oncotarget. 2018 Feb 3;9(13):10830-10831. doi: 10.18632/oncotarget.24395. eCollection 2018 Feb 16.
Oncotarget. 2018.
PMID: 29541378
Free PMC article.
No abstract available.
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Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase ε.
Sviderskiy VO, Blumenberg L, Gorodetsky E, Karakousi TR, Hirsh N, Alvarez SW, Terzi EM, Kaparos E, Whiten GC, Ssebyala S, Tonzi P, Mir H, Neel BG, Huang TT, Adams S, Ruggles KV, Possemato R.
Sviderskiy VO, et al. Among authors: alvarez sw.
Mol Cell. 2020 Nov 19;80(4):682-698.e7. doi: 10.1016/j.molcel.2020.10.016. Epub 2020 Nov 4.
Mol Cell. 2020.
PMID: 33152268
Free PMC article.
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Iron-sulfur cluster deficiency can be sensed by IRP2 and regulates iron homeostasis and sensitivity to ferroptosis independent of IRP1 and FBXL5.
Terzi EM, Sviderskiy VO, Alvarez SW, Whiten GC, Possemato R.
Terzi EM, et al. Among authors: alvarez sw.
Sci Adv. 2021 May 26;7(22):eabg4302. doi: 10.1126/sciadv.abg4302. Print 2021 May.
Sci Adv. 2021.
PMID: 34039609
Free PMC article.
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