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Page 1
CRISPR/Cas9 library screening for drug target discovery.
Kurata M, Yamamoto K, Moriarity BS, Kitagawa M, Largaespada DA. Kurata M, et al. Among authors: largaespada da. J Hum Genet. 2018 Feb;63(2):179-186. doi: 10.1038/s10038-017-0376-9. Epub 2017 Nov 20. J Hum Genet. 2018. PMID: 29158600 Review.
Efficient transposition of Tol2 in the mouse germline.
Keng VW, Ryan BJ, Wangensteen KJ, Balciunas D, Schmedt C, Ekker SC, Largaespada DA. Keng VW, et al. Among authors: largaespada da. Genetics. 2009 Dec;183(4):1565-73. doi: 10.1534/genetics.109.100768. Epub 2009 Oct 5. Genetics. 2009. PMID: 19805821 Free PMC article.
Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR.
Keng VW, Sia D, Sarver AL, Tschida BR, Fan D, Alsinet C, Solé M, Lee WL, Kuka TP, Moriarity BS, Villanueva A, Dupuy AJ, Riordan JD, Bell JB, Silverstein KA, Llovet JM, Largaespada DA. Keng VW, et al. Among authors: largaespada da. Hepatology. 2013 Jan;57(1):120-30. doi: 10.1002/hep.26004. Epub 2012 Oct 19. Hepatology. 2013. PMID: 22899566 Free PMC article.
Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenance.
Watson AL, Rahrmann EP, Moriarity BS, Choi K, Conboy CB, Greeley AD, Halfond AL, Anderson LK, Wahl BR, Keng VW, Rizzardi AE, Forster CL, Collins MH, Sarver AL, Wallace MR, Schmechel SC, Ratner N, Largaespada DA. Watson AL, et al. Among authors: largaespada da. Cancer Discov. 2013 Jun;3(6):674-89. doi: 10.1158/2159-8290.CD-13-0081. Epub 2013 Mar 27. Cancer Discov. 2013. PMID: 23535903 Free PMC article.
Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis.
Rahrmann EP, Watson AL, Keng VW, Choi K, Moriarity BS, Beckmann DA, Wolf NK, Sarver A, Collins MH, Moertel CL, Wallace MR, Gel B, Serra E, Ratner N, Largaespada DA. Rahrmann EP, et al. Among authors: largaespada da. Nat Genet. 2013 Jul;45(7):756-66. doi: 10.1038/ng.2641. Epub 2013 May 19. Nat Genet. 2013. PMID: 23685747 Free PMC article.
Simple and efficient methods for enrichment and isolation of endonuclease modified cells.
Moriarity BS, Rahrmann EP, Beckmann DA, Conboy CB, Watson AL, Carlson DF, Olson ER, Hyland KA, Fahrenkrug SC, McIvor RS, Largaespada DA. Moriarity BS, et al. Among authors: largaespada da. PLoS One. 2014 May 5;9(5):e96114. doi: 10.1371/journal.pone.0096114. eCollection 2014. PLoS One. 2014. PMID: 24798371 Free PMC article.
Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis.
Rahrmann EP, Moriarity BS, Otto GM, Watson AL, Choi K, Collins MH, Wallace M, Webber BR, Forster CL, Rizzardi AE, Schmechel SC, Ratner N, Largaespada DA. Rahrmann EP, et al. Among authors: largaespada da. Am J Pathol. 2014 Jul;184(7):2082-98. doi: 10.1016/j.ajpath.2014.04.006. Epub 2014 May 13. Am J Pathol. 2014. PMID: 24832557 Free PMC article.
237 results