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The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis.
Fusella F, Seclì L, Busso E, Krepelova A, Moiso E, Rocca S, Conti L, Annaratone L, Rubinetto C, Mello-Grand M, Singh V, Chiorino G, Silengo L, Altruda F, Turco E, Morotti A, Oliviero S, Castellano I, Cavallo F, Provero P, Tarone G, Brancaccio M. Fusella F, et al. Among authors: morotti a. Nat Commun. 2017 Nov 21;8(1):1636. doi: 10.1038/s41467-017-01829-1. Nat Commun. 2017. PMID: 29158506 Free PMC article.
Morgana acts as an oncosuppressor in chronic myeloid leukemia.
Di Savino A, Panuzzo C, Rocca S, Familiari U, Piazza R, Crivellaro S, Carrà G, Ferretti R, Fusella F, Giugliano E, Camporeale A, Franco I, Miniscalco B, Cutrin JC, Turco E, Silengo L, Hirsch E, Rege-Cambrin G, Gambacorti-Passerini C, Pandolfi PP, Papotti M, Saglio G, Tarone G, Morotti A, Brancaccio M. Di Savino A, et al. Among authors: morotti a. Blood. 2015 Apr 2;125(14):2245-53. doi: 10.1182/blood-2014-05-575001. Epub 2015 Feb 12. Blood. 2015. PMID: 25678499 Free article.
Deep Sequencing Reveals a Novel miR-22 Regulatory Network with Therapeutic Potential in Rhabdomyosarcoma.
Bersani F, Lingua MF, Morena D, Foglizzo V, Miretti S, Lanzetti L, Carrà G, Morotti A, Ala U, Provero P, Chiarle R, Singer S, Ladanyi M, Tuschl T, Ponzetto C, Taulli R. Bersani F, et al. Among authors: morotti a. Cancer Res. 2016 Oct 15;76(20):6095-6106. doi: 10.1158/0008-5472.CAN-16-0709. Epub 2016 Aug 28. Cancer Res. 2016. PMID: 27569217 Free PMC article.
Therapeutic inhibition of USP7-PTEN network in chronic lymphocytic leukemia: a strategy to overcome TP53 mutated/deleted clones.
Carrà G, Panuzzo C, Torti D, Parvis G, Crivellaro S, Familiari U, Volante M, Morena D, Lingua MF, Brancaccio M, Guerrasio A, Pandolfi PP, Saglio G, Taulli R, Morotti A. Carrà G, et al. Among authors: morotti a. Oncotarget. 2017 May 30;8(22):35508-35522. doi: 10.18632/oncotarget.16348. Oncotarget. 2017. PMID: 28418900 Free PMC article.
SETBP1 induces transcription of a network of development genes by acting as an epigenetic hub.
Piazza R, Magistroni V, Redaelli S, Mauri M, Massimino L, Sessa A, Peronaci M, Lalowski M, Soliymani R, Mezzatesta C, Pirola A, Banfi F, Rubio A, Rea D, Stagno F, Usala E, Martino B, Campiotti L, Merli M, Passamonti F, Onida F, Morotti A, Pavesi F, Bregni M, Broccoli V, Baumann M, Gambacorti-Passerini C. Piazza R, et al. Among authors: morotti a. Nat Commun. 2018 Jun 6;9(1):2192. doi: 10.1038/s41467-018-04462-8. Nat Commun. 2018. PMID: 29875417 Free PMC article.
263 results