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Discovering cancer vulnerabilities using high-throughput micro-RNA screening.
Nikolic I, Elsworth B, Dodson E, Wu SZ, Gould CM, Mestdagh P, Marshall GM, Horvath LG, Simpson KJ, Swarbrick A. Nikolic I, et al. Among authors: horvath lg. Nucleic Acids Res. 2017 Dec 15;45(22):12657-12670. doi: 10.1093/nar/gkx1072. Nucleic Acids Res. 2017. PMID: 29156009 Free PMC article.
Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer.
Valdés-Mora F, Gould CM, Colino-Sanguino Y, Qu W, Song JZ, Taylor KM, Buske FA, Statham AL, Nair SS, Armstrong NJ, Kench JG, Lee KML, Horvath LG, Qiu M, Ilinykh A, Yeo-Teh NS, Gallego-Ortega D, Stirzaker C, Clark SJ. Valdés-Mora F, et al. Among authors: horvath lg. Nat Commun. 2017 Nov 7;8(1):1346. doi: 10.1038/s41467-017-01393-8. Nat Commun. 2017. PMID: 29116202 Free PMC article.
DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns.
Skvortsova K, Masle-Farquhar E, Luu PL, Song JZ, Qu W, Zotenko E, Gould CM, Du Q, Peters TJ, Colino-Sanguino Y, Pidsley R, Nair SS, Khoury A, Smith GC, Miosge LA, Reed JH, Kench JG, Rubin MA, Horvath L, Bogdanovic O, Lim SM, Polo JM, Goodnow CC, Stirzaker C, Clark SJ. Skvortsova K, et al. Cancer Cell. 2019 Feb 11;35(2):297-314.e8. doi: 10.1016/j.ccell.2019.01.004. Cancer Cell. 2019. PMID: 30753827 Free article.
Expression of the zinc transporter ZnT4 is decreased in the progression from early prostate disease to invasive prostate cancer.
Henshall SM, Afar DE, Rasiah KK, Horvath LG, Gish K, Caras I, Ramakrishnan V, Wong M, Jeffry U, Kench JG, Quinn DI, Turner JJ, Delprado W, Lee CS, Golovsky D, Brenner PC, O'Neill GF, Kooner R, Stricker PD, Grygiel JJ, Mack DH, Sutherland RL. Henshall SM, et al. Among authors: horvath lg. Oncogene. 2003 Sep 4;22(38):6005-12. doi: 10.1038/sj.onc.1206797. Oncogene. 2003. PMID: 12955079
141 results