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GZD824 suppresses the growth of human B cell precursor acute lymphoblastic leukemia cells by inhibiting the SRC kinase and PI3K/AKT pathways.
Ye W, Jiang Z, Lu X, Ren X, Deng M, Lin S, Xiao Y, Lin S, Wang S, Li B, Zheng Y, Lai P, Weng J, Wu D, Ma Y, Chen X, Wen Z, Chen Y, Feng X, Li Y, Liu P, Du X, Pei D, Yao Y, Xu B, Ding K, Li P. Ye W, et al. Among authors: zheng y. Oncotarget. 2016 Jul 28;8(50):87002-87015. doi: 10.18632/oncotarget.10881. eCollection 2017 Oct 20. Oncotarget. 2016. PMID: 29152059 Free PMC article.
Lentivirus-mediated RNA interference targeting FAMLF-1 inhibits cell growth and enhances cell differentiation of acute myeloid leukemia partially differentiated cells via inhibition of AKT and c-MYC.
Huang YM, Zheng Y, Li JG, Wang XC, Wang ZC, Chen WL, Pan LL, Li Y, Luo DF, Wang SY. Huang YM, et al. Among authors: zheng y. Oncotarget. 2017 Sep 26;8(60):101372-101382. doi: 10.18632/oncotarget.21276. eCollection 2017 Nov 24. Oncotarget. 2017. PMID: 29254171 Free PMC article.
DHX15 is associated with poor prognosis in acute myeloid leukemia (AML) and regulates cell apoptosis via the NF-kB signaling pathway.
Pan L, Li Y, Zhang HY, Zheng Y, Liu XL, Hu Z, Wang Y, Wang J, Cai YH, Liu Q, Chen WL, Guo Y, Huang YM, Qian F, Jin L, Wang J, Wang SY. Pan L, et al. Among authors: zheng y. Oncotarget. 2017 Aug 16;8(52):89643-89654. doi: 10.18632/oncotarget.20288. eCollection 2017 Oct 27. Oncotarget. 2017. PMID: 29163777 Free PMC article.
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