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Controlled Fab-arm exchange for the generation of stable bispecific IgG1.
Labrijn AF, Meesters JI, Priem P, de Jong RN, van den Bremer ET, van Kampen MD, Gerritsen AF, Schuurman J, Parren PW. Labrijn AF, et al. Among authors: de jong rn. Nat Protoc. 2014 Oct;9(10):2450-63. doi: 10.1038/nprot.2014.169. Epub 2014 Sep 25. Nat Protoc. 2014. PMID: 25255089
Cysteine-SILAC Mass Spectrometry Enabling the Identification and Quantitation of Scrambled Interchain Disulfide Bonds: Preservation of Native Heavy-Light Chain Pairing in Bispecific IgGs Generated by Controlled Fab-arm Exchange.
van den Bremer ETJ, Labrijn AF, van den Boogaard R, Priem P, Scheffler K, Melis JPM, Schuurman J, Parren PWHI, de Jong RN. van den Bremer ETJ, et al. Among authors: de jong rn. Anal Chem. 2017 Oct 17;89(20):10873-10882. doi: 10.1021/acs.analchem.7b02543. Epub 2017 Oct 2. Anal Chem. 2017. PMID: 28922593
Functional analysis of the anti-adalimumab response using patient-derived monoclonal antibodies.
van Schouwenburg PA, Kruithof S, Votsmeier C, van Schie K, Hart MH, de Jong RN, van Buren EE, van Ham M, Aarden L, Wolbink G, Wouters D, Rispens T. van Schouwenburg PA, et al. Among authors: de jong rn. J Biol Chem. 2014 Dec 12;289(50):34482-8. doi: 10.1074/jbc.M114.615500. Epub 2014 Oct 17. J Biol Chem. 2014. PMID: 25326381 Free PMC article. Review.
Adalimumab elicits a restricted anti-idiotypic antibody response in autoimmune patients resulting in functional neutralisation.
van Schouwenburg PA, van de Stadt LA, de Jong RN, van Buren EE, Kruithof S, de Groot E, Hart M, van Ham SM, Rispens T, Aarden L, Wolbink GJ, Wouters D. van Schouwenburg PA, et al. Among authors: de jong rn, de groot e. Ann Rheum Dis. 2013 Jan;72(1):104-9. doi: 10.1136/annrheumdis-2012-201445. Epub 2012 Jul 3. Ann Rheum Dis. 2013. PMID: 22759910
CD20 and CD37 antibodies synergize to activate complement by Fc-mediated clustering.
Oostindie SC, van der Horst HJ, Lindorfer MA, Cook EM, Tupitza JC, Zent CS, Burack R, VanDerMeid KR, Strumane K, Chamuleau MED, Mutis T, de Jong RN, Schuurman J, Breij ECW, Beurskens FJ, Parren PWHI, Taylor RP. Oostindie SC, et al. Among authors: de jong rn. Haematologica. 2019 Sep;104(9):1841-1852. doi: 10.3324/haematol.2018.207266. Epub 2019 Feb 21. Haematologica. 2019. PMID: 30792198 Free PMC article.
75 results