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An unexpected protein interaction promotes drug resistance in leukemia.
Pitre A, Ge Y, Lin W, Wang Y, Fukuda Y, Temirov J, Phillips AH, Peters JL, Fan Y, Ma J, Nourse A, Sinha C, Lin H, Kriwacki R, Downing JR, Gruber TA, Centonze VE, Naren AP, Chen T, Schuetz JD. Pitre A, et al. Among authors: schuetz jd. Nat Commun. 2017 Nov 16;8(1):1547. doi: 10.1038/s41467-017-01678-y. Nat Commun. 2017. PMID: 29146910 Free PMC article.
Leukemia and ABC transporters.
Fukuda Y, Lian S, Schuetz JD. Fukuda Y, et al. Among authors: schuetz jd. Adv Cancer Res. 2015;125:171-96. doi: 10.1016/bs.acr.2014.10.006. Epub 2015 Jan 8. Adv Cancer Res. 2015. PMID: 25640270 Free PMC article. Review.
Maternal bile acid transporter deficiency promotes neonatal demise.
Zhang Y, Li F, Wang Y, Pitre A, Fang ZZ, Frank MW, Calabrese C, Krausz KW, Neale G, Frase S, Vogel P, Rock CO, Gonzalez FJ, Schuetz JD. Zhang Y, et al. Among authors: schuetz jd. Nat Commun. 2015 Sep 29;6:8186. doi: 10.1038/ncomms9186. Nat Commun. 2015. PMID: 26416771 Free PMC article.
Compartmentalized accumulation of cAMP near complexes of multidrug resistance protein 4 (MRP4) and cystic fibrosis transmembrane conductance regulator (CFTR) contributes to drug-induced diarrhea.
Moon C, Zhang W, Ren A, Arora K, Sinha C, Yarlagadda S, Woodrooffe K, Schuetz JD, Valasani KR, de Jonge HR, Shanmukhappa SK, Shata MT, Buddington RK, Parthasarathi K, Naren AP. Moon C, et al. Among authors: schuetz jd. J Biol Chem. 2015 May 1;290(18):11246-57. doi: 10.1074/jbc.M114.605410. Epub 2015 Mar 11. J Biol Chem. 2015. PMID: 25762723 Free PMC article.
The ABCC4 membrane transporter modulates platelet aggregation.
Cheepala SB, Pitre A, Fukuda Y, Takenaka K, Zhang Y, Wang Y, Frase S, Pestina T, Gartner TK, Jackson C, Schuetz JD. Cheepala SB, et al. Among authors: schuetz jd. Blood. 2015 Nov 12;126(20):2307-19. doi: 10.1182/blood-2014-08-595942. Epub 2015 Sep 24. Blood. 2015. PMID: 26405223 Free PMC article.
190 results