Ge Y - Search Results

1

An unexpected protein interaction promotes drug resistance in leukemia.

Pitre A, Ge Y, Lin W, Wang Y, Fukuda Y, Temirov J, Phillips AH, Peters JL, Fan Y, Ma J, Nourse A, Sinha C, Lin H, Kriwacki R, Downing JR, Gruber TA, Centonze VE, Naren AP, Chen T, Schuetz JD. Pitre A, et al. Among authors: ge y. Nat Commun. 2017 Nov 16;8(1):1547. doi: 10.1038/s41467-017-01678-y. Nat Commun. 2017. PMID: 29146910 Free PMC article.

2

Acute myeloid leukemia cells harboring MLL fusion genes or with the acute promyelocytic leukemia phenotype are sensitive to the Bcl-2-selective inhibitor ABT-199.

Niu X, Wang G, Wang Y, Caldwell JT, Edwards H, Xie C, Taub JW, Li C, Lin H, Ge Y. Niu X, et al. Among authors: ge y. Leukemia. 2014 Jul;28(7):1557-60. doi: 10.1038/leu.2014.72. Epub 2014 Feb 17. Leukemia. 2014. PMID: 24531733 Free PMC article. No abstract available.

3

CHK1 plays a critical role in the anti-leukemic activity of the wee1 inhibitor MK-1775 in acute myeloid leukemia cells.

Qi W, Xie C, Li C, Caldwell JT, Edwards H, Taub JW, Wang Y, Lin H, Ge Y. Qi W, et al. Among authors: ge y. J Hematol Oncol. 2014 Aug 1;7:53. doi: 10.1186/s13045-014-0053-9. J Hematol Oncol. 2014. PMID: 25084614 Free PMC article.

4

Obatoclax potentiates the cytotoxic effect of cytarabine on acute myeloid leukemia cells by enhancing DNA damage.

Xie C, Edwards H, Caldwell JT, Wang G, Taub JW, Ge Y. Xie C, et al. Among authors: ge y. Mol Oncol. 2015 Feb;9(2):409-21. doi: 10.1016/j.molonc.2014.09.008. Epub 2014 Oct 2. Mol Oncol. 2015. PMID: 25308513 Free PMC article.

5

Synergistic anti-leukemic interactions between panobinostat and MK-1775 in acute myeloid leukemia ex vivo.

Qi W, Zhang W, Edwards H, Chu R, Madlambayan GJ, Taub JW, Wang Z, Wang Y, Li C, Lin H, Ge Y. Qi W, et al. Among authors: ge y. Cancer Biol Ther. 2015;16(12):1784-93. doi: 10.1080/15384047.2015.1095406. Cancer Biol Ther. 2015. PMID: 26529495 Free PMC article.

6

Binding of Released Bim to Mcl-1 is a Mechanism of Intrinsic Resistance to ABT-199 which can be Overcome by Combination with Daunorubicin or Cytarabine in AML Cells.

Niu X, Zhao J, Ma J, Xie C, Edwards H, Wang G, Caldwell JT, Xiang S, Zhang X, Chu R, Wang ZJ, Lin H, Taub JW, Ge Y. Niu X, et al. Among authors: ge y. Clin Cancer Res. 2016 Sep 1;22(17):4440-51. doi: 10.1158/1078-0432.CCR-15-3057. Epub 2016 Apr 21. Clin Cancer Res. 2016. PMID: 27103402 Free PMC article.

7

Inhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells.

Zhao J, Niu X, Li X, Edwards H, Wang G, Wang Y, Taub JW, Lin H, Ge Y. Zhao J, et al. Among authors: ge y. Oncotarget. 2016 Jun 7;7(23):34785-99. doi: 10.18632/oncotarget.9185. Oncotarget. 2016. PMID: 27166183 Free PMC article.

8

Synthesis and Antileukemic Activities of Piperlongumine and HDAC Inhibitor Hybrids against Acute Myeloid Leukemia Cells.

Liao Y, Niu X, Chen B, Edwards H, Xu L, Xie C, Lin H, Polin L, Taub JW, Ge Y, Qin Z. Liao Y, et al. Among authors: ge y. J Med Chem. 2016 Sep 8;59(17):7974-90. doi: 10.1021/acs.jmedchem.6b00772. Epub 2016 Aug 24. J Med Chem. 2016. PMID: 27505848 Free PMC article.

9

Synergistic anti-leukemic interactions between ABT-199 and panobinostat in acute myeloid leukemia ex vivo.

Schwartz J, Niu X, Walton E, Hurley L, Lin H, Edwards H, Taub JW, Wang Z, Ge Y. Schwartz J, et al. Among authors: ge y. Am J Transl Res. 2016 Sep 15;8(9):3893-3902. eCollection 2016. Am J Transl Res. 2016. PMID: 27725868 Free PMC article.

10

Mechanisms responsible for the synergistic antileukemic interactions between ATR inhibition and cytarabine in acute myeloid leukemia cells.

Ma J, Li X, Su Y, Zhao J, Luedtke DA, Epshteyn V, Edwards H, Wang G, Wang Z, Chu R, Taub JW, Lin H, Wang Y, Ge Y. Ma J, et al. Among authors: ge y. Sci Rep. 2017 Feb 8;7:41950. doi: 10.1038/srep41950. Sci Rep. 2017. PMID: 28176818 Free PMC article.

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