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PD-L1 genetic overexpression or pharmacological restoration in hematopoietic stem and progenitor cells reverses autoimmune diabetes.
Ben Nasr M, Tezza S, D'Addio F, Mameli C, Usuelli V, Maestroni A, Corradi D, Belletti S, Albarello L, Becchi G, Fadini GP, Schuetz C, Markmann J, Wasserfall C, Zon L, Zuccotti GV, Fiorina P. Ben Nasr M, et al. Among authors: zon l. Sci Transl Med. 2017 Nov 15;9(416):eaam7543. doi: 10.1126/scitranslmed.aam7543. Sci Transl Med. 2017. PMID: 29141886 Free PMC article.
The transcriptional landscape of hematopoietic stem cell ontogeny.
McKinney-Freeman S, Cahan P, Li H, Lacadie SA, Huang HT, Curran M, Loewer S, Naveiras O, Kathrein KL, Konantz M, Langdon EM, Lengerke C, Zon LI, Collins JJ, Daley GQ. McKinney-Freeman S, et al. Among authors: zon li. Cell Stem Cell. 2012 Nov 2;11(5):701-14. doi: 10.1016/j.stem.2012.07.018. Cell Stem Cell. 2012. PMID: 23122293 Free PMC article.
Adenosine signaling promotes hematopoietic stem and progenitor cell emergence.
Jing L, Tamplin OJ, Chen MJ, Deng Q, Patterson S, Kim PG, Durand EM, McNeil A, Green JM, Matsuura S, Ablain J, Brandt MK, Schlaeger TM, Huttenlocher A, Daley GQ, Ravid K, Zon LI. Jing L, et al. Among authors: zon li. J Exp Med. 2015 May 4;212(5):649-63. doi: 10.1084/jem.20141528. Epub 2015 Apr 13. J Exp Med. 2015. PMID: 25870200 Free PMC article.
Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease.
Burberry A, Suzuki N, Wang JY, Moccia R, Mordes DA, Stewart MH, Suzuki-Uematsu S, Ghosh S, Singh A, Merkle FT, Koszka K, Li QZ, Zon L, Rossi DJ, Trowbridge JJ, Notarangelo LD, Eggan K. Burberry A, et al. Among authors: zon l. Sci Transl Med. 2016 Jul 13;8(347):347ra93. doi: 10.1126/scitranslmed.aaf6038. Sci Transl Med. 2016. PMID: 27412785 Free PMC article.
Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors.
Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee HY, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, Agarwal S, Ebert BL, Gazda HT, Lodish HF, Sieff CA, Schlaeger TM, Zon LI, Daley GQ. Doulatov S, et al. Among authors: zon li. Sci Transl Med. 2017 Feb 8;9(376):eaah5645. doi: 10.1126/scitranslmed.aah5645. Sci Transl Med. 2017. PMID: 28179501 Free PMC article.
549 results