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Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead.
Bondeson DP, Smith BE, Burslem GM, Buhimschi AD, Hines J, Jaime-Figueroa S, Wang J, Hamman BD, Ishchenko A, Crews CM. Bondeson DP, et al. Among authors: burslem gm. Cell Chem Biol. 2018 Jan 18;25(1):78-87.e5. doi: 10.1016/j.chembiol.2017.09.010. Epub 2017 Nov 9. Cell Chem Biol. 2018. PMID: 29129718 Free PMC article.
Small-Molecule Modulation of Protein Homeostasis.
Burslem GM, Crews CM. Burslem GM, et al. Chem Rev. 2017 Sep 13;117(17):11269-11301. doi: 10.1021/acs.chemrev.7b00077. Epub 2017 Aug 4. Chem Rev. 2017. PMID: 28777566 Review.
The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study.
Burslem GM, Smith BE, Lai AC, Jaime-Figueroa S, McQuaid DC, Bondeson DP, Toure M, Dong H, Qian Y, Wang J, Crew AP, Hines J, Crews CM. Burslem GM, et al. Cell Chem Biol. 2018 Jan 18;25(1):67-77.e3. doi: 10.1016/j.chembiol.2017.09.009. Epub 2017 Nov 9. Cell Chem Biol. 2018. PMID: 29129716 Free PMC article.
Protein folding state-dependent sorting at the Golgi apparatus.
Hellerschmied D, Serebrenik YV, Shao L, Burslem GM, Crews CM. Hellerschmied D, et al. Among authors: burslem gm. Mol Biol Cell. 2019 Aug 1;30(17):2296-2308. doi: 10.1091/mbc.E19-01-0069. Epub 2019 Jun 5. Mol Biol Cell. 2019. PMID: 31166830 Free PMC article.
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