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Efficacy of hepatitis B virus ribonuclease H inhibitors, a new class of replication antagonists, in FRG human liver chimeric mice.
Antiviral Res. 2018 Jan;149:41-47. doi: 10.1016/j.antiviral.2017.11.008. Epub 2017 Nov 10.
Antiviral Res. 2018.
PMID: 29129708
Free PMC article.
Shedding light on RNaseH: a promising target for hepatitis B virus (HBV).
Edwards TC, Ponzar NL, Tavis JE.
Edwards TC, et al. Among authors: ponzar nl.
Expert Opin Ther Targets. 2019 Jul;23(7):559-563. doi: 10.1080/14728222.2019.1619697. Epub 2019 May 22.
Expert Opin Ther Targets. 2019.
PMID: 31084514
Free PMC article.
No abstract available.
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A mid-throughput HBV replication inhibition assay capable of detecting ribonuclease H inhibitors.
Li Q, Edwards TC, Ponzar NL, Tavis JE.
Li Q, et al. Among authors: ponzar nl.
J Virol Methods. 2021 Jun;292:114127. doi: 10.1016/j.jviromet.2021.114127. Epub 2021 Mar 22.
J Virol Methods. 2021.
PMID: 33766659
Free PMC article.
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Effects of Troponoids on Mitochondrial Function and Cytotoxicity.
Bradley DP, O'Dea AT, Woodson ME, Li Q, Ponzar NL, Knier A, Rogers BL, Murelli RP, Tavis JE.
Bradley DP, et al. Among authors: ponzar nl.
Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0161721. doi: 10.1128/AAC.01617-21. Epub 2021 Oct 25.
Antimicrob Agents Chemother. 2022.
PMID: 34694883
Free PMC article.
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Alpha-hydroxytropolones are noncompetitive inhibitors of human RNase H1 that bind to the active site and modulate substrate binding.
Ponzar NL, Tajwar R, Pozzi N, Tavis JE.
Ponzar NL, et al.
J Biol Chem. 2022 Apr;298(4):101790. doi: 10.1016/j.jbc.2022.101790. Epub 2022 Mar 3.
J Biol Chem. 2022.
PMID: 35247386
Free PMC article.
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Predicted structure of the hepatitis B virus polymerase reveals an ancient conserved protein fold.
Tajwar R, Bradley DP, Ponzar NL, Tavis JE.
Tajwar R, et al. Among authors: ponzar nl.
Protein Sci. 2022 Oct;31(10):e4421. doi: 10.1002/pro.4421.
Protein Sci. 2022.
PMID: 36173165
Free PMC article.
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Probing the conformational dynamics of thiol-isomerases using non-canonical amino acids and single-molecule FRET.
Ponzar N, Pozzi N.
Ponzar N, et al.
Methods. 2023 Jun;214:8-17. doi: 10.1016/j.ymeth.2023.04.004. Epub 2023 Apr 15.
Methods. 2023.
PMID: 37068599
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