Oren YS - Search Results

1

The suppression of premature termination codons and the repair of splicing mutations in CFTR.

Oren YS, Pranke IM, Kerem B, Sermet-Gaudelus I. Oren YS, et al. Curr Opin Pharmacol. 2017 Jun;34:125-131. doi: 10.1016/j.coph.2017.09.017. Epub 2017 Nov 10. Curr Opin Pharmacol. 2017. PMID: 29128743 Review.

2

Nonsense-mediated mRNA decay affects nonsense transcript levels and governs response of cystic fibrosis patients to gentamicin.

Linde L, Boelz S, Nissim-Rafinia M, Oren YS, Wilschanski M, Yaacov Y, Virgilis D, Neu-Yilik G, Kulozik AE, Kerem E, Kerem B. Linde L, et al. Among authors: oren ys. J Clin Invest. 2007 Mar;117(3):683-92. doi: 10.1172/JCI28523. Epub 2007 Feb 8. J Clin Invest. 2007. PMID: 17290305 Free PMC article.

3

Impaired replication stress response in cells from immunodeficiency patients carrying Cernunnos/XLF mutations.

Schwartz M, Oren YS, Bester AC, Rahat A, Sfez R, Yitzchaik S, de Villartay JP, Kerem B. Schwartz M, et al. Among authors: oren ys. PLoS One. 2009;4(2):e4516. doi: 10.1371/journal.pone.0004516. Epub 2009 Feb 18. PLoS One. 2009. PMID: 19223975 Free PMC article.

4

Nucleotide deficiency promotes genomic instability in early stages of cancer development.

Bester AC, Roniger M, Oren YS, Im MM, Sarni D, Chaoat M, Bensimon A, Zamir G, Shewach DS, Kerem B. Bester AC, et al. Among authors: oren ys. Cell. 2011 Apr 29;145(3):435-46. doi: 10.1016/j.cell.2011.03.044. Cell. 2011. PMID: 21529715 Free PMC article.

5

The unfolded protein response affects readthrough of premature termination codons.

Oren YS, McClure ML, Rowe SM, Sorscher EJ, Bester AC, Manor M, Kerem E, Rivlin J, Zahdeh F, Mann M, Geiger T, Kerem B. Oren YS, et al. EMBO Mol Med. 2014 May;6(5):685-701. doi: 10.1002/emmm.201303347. EMBO Mol Med. 2014. PMID: 24705877 Free PMC article.

6

Take it personally: how personal we reach when we are so different from each other?

Kerem E, Oren YS, Kerem B. Kerem E, et al. Among authors: oren ys. J Cyst Fibros. 2019 Jan;18(1):6-7. doi: 10.1016/j.jcf.2018.12.009. J Cyst Fibros. 2019. PMID: 30665545 Free article. No abstract available.

7

New approaches to genetic therapies for cystic fibrosis.

Christopher Boyd A, Guo S, Huang L, Kerem B, Oren YS, Walker AJ, Hart SL. Christopher Boyd A, et al. Among authors: oren ys. J Cyst Fibros. 2020 Mar;19 Suppl 1:S54-S59. doi: 10.1016/j.jcf.2019.12.012. Epub 2020 Jan 13. J Cyst Fibros. 2020. PMID: 31948871 Free article. Review.

8

Antisense oligonucleotide-based drug development for Cystic Fibrosis patients carrying the 3849+10 kb C-to-T splicing mutation.

Oren YS, Irony-Tur Sinai M, Golec A, Barchad-Avitzur O, Mutyam V, Li Y, Hong J, Ozeri-Galai E, Hatton A, Leibson C, Carmel L, Reiter J, Sorscher EJ, Wilton SD, Kerem E, Rowe SM, Sermet-Gaudelus I, Kerem B. Oren YS, et al. J Cyst Fibros. 2021 Sep;20(5):865-875. doi: 10.1016/j.jcf.2021.06.003. Epub 2021 Jul 2. J Cyst Fibros. 2021. PMID: 34226157 Free PMC article.

9

Antisense oligonucleotide splicing modulation as a novel Cystic Fibrosis therapeutic approach for the W1282X nonsense mutation.

Oren YS, Avizur-Barchad O, Ozeri-Galai E, Elgrabli R, Schirelman MR, Blinder T, Stampfer CD, Ordan M, Laselva O, Cohen-Cymberknoh M, Kerem E, Bear CE, Kerem B. Oren YS, et al. J Cyst Fibros. 2022 Jul;21(4):630-636. doi: 10.1016/j.jcf.2021.12.012. Epub 2021 Dec 28. J Cyst Fibros. 2022. PMID: 34972649 Free article.

10

Topoisomerase 1-dependent R-loop deficiency drives accelerated replication and genomic instability.

Sarni D, Barroso S, Shtrikman A, Irony-Tur Sinai M, Oren YS, Aguilera A, Kerem B. Sarni D, et al. Among authors: oren ys. Cell Rep. 2022 Sep 27;40(13):111397. doi: 10.1016/j.celrep.2022.111397. Cell Rep. 2022. PMID: 36170822 Free PMC article.

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