Liesenfeld KH - Search Results

1

Population pharmacokinetics of nintedanib, an inhibitor of tyrosine kinases, in patients with non-small cell lung cancer or idiopathic pulmonary fibrosis.

Schmid U, Liesenfeld KH, Fleury A, Dallinger C, Freiwald M. Schmid U, et al. Among authors: liesenfeld kh. Cancer Chemother Pharmacol. 2018 Jan;81(1):89-101. doi: 10.1007/s00280-017-3452-0. Epub 2017 Nov 8. Cancer Chemother Pharmacol. 2018. PMID: 29119292 Free PMC article.

2

Effects of the direct thrombin inhibitor dabigatran on ex vivo coagulation time in orthopaedic surgery patients: a population model analysis.

Liesenfeld KH, Schäfer HG, Trocóniz IF, Tillmann C, Eriksson BI, Stangier J. Liesenfeld KH, et al. Br J Clin Pharmacol. 2006 Nov;62(5):527-37. doi: 10.1111/j.1365-2125.2006.02667.x. Br J Clin Pharmacol. 2006. PMID: 17061960 Free PMC article.

3

Population pharmacokinetic analysis of the new oral thrombin inhibitor dabigatran etexilate (BIBR 1048) in patients undergoing primary elective total hip replacement surgery.

Trocóniz IF, Tillmann C, Liesenfeld KH, Schäfer HG, Stangier J. Trocóniz IF, et al. Among authors: liesenfeld kh. J Clin Pharmacol. 2007 Mar;47(3):371-82. doi: 10.1177/0091270006297228. J Clin Pharmacol. 2007. PMID: 17322149 Clinical Trial.

4

Population pharmacokinetics of tamsulosin hydrochloride in paediatric patients with neuropathic and non-neuropathic bladder.

Tsuda Y, Tatami S, Yamamura N, Tadayasu Y, Sarashina A, Liesenfeld KH, Staab A, Schäfer HG, Ieiri I, Higuchi S. Tsuda Y, et al. Among authors: liesenfeld kh. Br J Clin Pharmacol. 2010 Jul;70(1):88-101. doi: 10.1111/j.1365-2125.2010.03662.x. Br J Clin Pharmacol. 2010. PMID: 20642551 Free PMC article. Clinical Trial.

5

Dabigatran etexilate in atrial fibrillation patients with severe renal impairment: dose identification using pharmacokinetic modeling and simulation.

Lehr T, Haertter S, Liesenfeld KH, Staab A, Clemens A, Reilly PA, Friedman J. Lehr T, et al. Among authors: liesenfeld kh. J Clin Pharmacol. 2012 Sep;52(9):1373-8. doi: 10.1177/0091270011417716. Epub 2011 Sep 28. J Clin Pharmacol. 2012. PMID: 21956604

6

Enhanced elimination of dabigatran: Identifying the appropriate patient for the use of continuous venovenous hemodialysis instead of intermittent hemodialysis-A simulation analysis.

Liesenfeld KH, Gruenenfelder F, Clemens A. Liesenfeld KH, et al. J Clin Pharmacol. 2016 May;56(5):597-608. doi: 10.1002/jcph.620. Epub 2015 Nov 5. J Clin Pharmacol. 2016. PMID: 26272714

7

Multiple Rising Doses of Oral BI 425809, a GlyT1 Inhibitor, in Young and Elderly Healthy Volunteers: A Randomised, Double-Blind, Phase I Study Investigating Safety and Pharmacokinetics.

Moschetti V, Schlecker C, Wind S, Goetz S, Schmitt H, Schultz A, Liesenfeld KH, Wunderlich G, Desch M. Moschetti V, et al. Among authors: liesenfeld kh. Clin Drug Investig. 2018 Aug;38(8):737-750. doi: 10.1007/s40261-018-0660-2. Clin Drug Investig. 2018. PMID: 29846887 Free PMC article. Clinical Trial.

8

Evaluation of Pharmacokinetics and Pharmacodynamics of BI 425809, a Novel GlyT1 Inhibitor: Translational Studies.

Rosenbrock H, Desch M, Kleiner O, Dorner-Ciossek C, Schmid B, Keller S, Schlecker C, Moschetti V, Goetz S, Liesenfeld KH, Fillon G, Giovannini R, Ramael S, Wunderlich G, Wind S. Rosenbrock H, et al. Among authors: liesenfeld kh. Clin Transl Sci. 2018 Nov;11(6):616-623. doi: 10.1111/cts.12578. Epub 2018 Aug 23. Clin Transl Sci. 2018. PMID: 30136756 Free PMC article. Clinical Trial.

9

Population pharmacokinetics of adalimumab biosimilar adalimumab-adbm and reference product in healthy subjects and patients with rheumatoid arthritis to assess pharmacokinetic similarity.

Kang J, Eudy-Byrne RJ, Mondick J, Knebel W, Jayadeva G, Liesenfeld KH. Kang J, et al. Among authors: liesenfeld kh. Br J Clin Pharmacol. 2020 Nov;86(11):2274-2285. doi: 10.1111/bcp.14330. Epub 2020 Jun 11. Br J Clin Pharmacol. 2020. PMID: 32363771 Free PMC article.

10

Effects of Cytochrome P450 3A4 Induction and Inhibition on the Pharmacokinetics of BI 425809, a Novel Glycine Transporter 1 Inhibitor.

Desch M, Wunderlich G, Goettel M, Goetz S, Liesenfeld KH, Chan TS, Rosenbrock H, Sennewald R, Link J, Keller S, Wind S. Desch M, et al. Among authors: liesenfeld kh. Eur J Drug Metab Pharmacokinet. 2022 Jan;47(1):91-103. doi: 10.1007/s13318-021-00723-y. Epub 2021 Oct 29. Eur J Drug Metab Pharmacokinet. 2022. PMID: 34716565 Free PMC article. Clinical Trial.

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