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Complement Activation via a C3a Receptor Pathway Alters CD4+ T Lymphocytes and Mediates Lung Cancer Progression.
Kwak JW, Laskowski J, Li HY, McSharry MV, Sippel TR, Bullock BL, Johnson AM, Poczobutt JM, Neuwelt AJ, Malkoski SP, Weiser-Evans MC, Lambris JD, Clambey ET, Thurman JM, Nemenoff RA. Kwak JW, et al. Among authors: johnson am. Cancer Res. 2018 Jan 1;78(1):143-156. doi: 10.1158/0008-5472.CAN-17-0240. Epub 2017 Nov 8. Cancer Res. 2018. PMID: 29118090 Free PMC article.
Targeted overexpression of prostacyclin synthase inhibits lung tumor progression by recruiting CD4+ T lymphocytes in tumors that express MHC class II.
Li HY, McSharry M, Walker D, Johnson A, Kwak J, Bullock B, Neuwelt A, Poczobutt JM, Sippel TR, Keith RL, Weiser-Evans MCM, Clambey E, Nemenoff RA. Li HY, et al. Oncoimmunology. 2018 Feb 13;7(5):e1423182. doi: 10.1080/2162402X.2017.1423182. eCollection 2018. Oncoimmunology. 2018. PMID: 29721380 Free PMC article.
Tumor-intrinsic response to IFNγ shapes the tumor microenvironment and anti-PD-1 response in NSCLC.
Bullock BL, Kimball AK, Poczobutt JM, Neuwelt AJ, Li HY, Johnson AM, Kwak JW, Kleczko EK, Kaspar RE, Wagner EK, Hopp K, Schenk EL, Weiser-Evans MC, Clambey ET, Nemenoff RA. Bullock BL, et al. Among authors: johnson am. Life Sci Alliance. 2019 May 27;2(3):e201900328. doi: 10.26508/lsa.201900328. Print 2019 Jun. Life Sci Alliance. 2019. PMID: 31133614 Free PMC article.
Cancer cell-intrinsic expression of MHC II in lung cancer cell lines is actively restricted by MEK/ERK signaling and epigenetic mechanisms.
Neuwelt AJ, Kimball AK, Johnson AM, Arnold BW, Bullock BL, Kaspar RE, Kleczko EK, Kwak JW, Wu MH, Heasley LE, Doebele RC, Li HY, Nemenoff RA, Clambey ET. Neuwelt AJ, et al. Among authors: johnson am. J Immunother Cancer. 2020 Apr;8(1):e000441. doi: 10.1136/jitc-2019-000441. J Immunother Cancer. 2020. PMID: 32312906 Free PMC article.
Eicosanoids in Cancer: New Roles in Immunoregulation.
Johnson AM, Kleczko EK, Nemenoff RA. Johnson AM, et al. Front Pharmacol. 2020 Nov 18;11:595498. doi: 10.3389/fphar.2020.595498. eCollection 2020. Front Pharmacol. 2020. PMID: 33364964 Free PMC article. Review.
Cancer Cell-Specific Major Histocompatibility Complex II Expression as a Determinant of the Immune Infiltrate Organization and Function in the NSCLC Tumor Microenvironment.
Johnson AM, Boland JM, Wrobel J, Klezcko EK, Weiser-Evans M, Hopp K, Heasley L, Clambey ET, Jordan K, Nemenoff RA, Schenk EL. Johnson AM, et al. J Thorac Oncol. 2021 Oct;16(10):1694-1704. doi: 10.1016/j.jtho.2021.05.004. Epub 2021 May 25. J Thorac Oncol. 2021. PMID: 34048945 Free PMC article.
1,384 results