Loftus JC - Search Results

1

A Novel Signaling Complex between TROY and EGFR Mediates Glioblastoma Cell Invasion.

Ding Z, Roos A, Kloss J, Dhruv H, Peng S, Pirrotte P, Eschbacher JM, Tran NL, Loftus JC. Ding Z, et al. Among authors: loftus jc. Mol Cancer Res. 2018 Feb;16(2):322-332. doi: 10.1158/1541-7786.MCR-17-0454. Epub 2017 Nov 8. Mol Cancer Res. 2018. PMID: 29117939 Free PMC article.

2

Differential role of proline-rich tyrosine kinase 2 and focal adhesion kinase in determining glioblastoma migration and proliferation.

Lipinski CA, Tran NL, Bay C, Kloss J, McDonough WS, Beaudry C, Berens ME, Loftus JC. Lipinski CA, et al. Among authors: loftus jc. Mol Cancer Res. 2003 Mar;1(5):323-32. Mol Cancer Res. 2003. PMID: 12651906

3

Tumor necrosis factor-like weak inducer of apoptosis stimulation of glioma cell survival is dependent on Akt2 function.

Fortin SP, Ennis MJ, Savitch BA, Carpentieri D, McDonough WS, Winkles JA, Loftus JC, Kingsley C, Hostetter G, Tran NL. Fortin SP, et al. Among authors: loftus jc. Mol Cancer Res. 2009 Nov;7(11):1871-81. doi: 10.1158/1541-7786.MCR-09-0194. Epub 2009 Oct 27. Mol Cancer Res. 2009. PMID: 19861406 Free PMC article.

4

TROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling.

Paulino VM, Yang Z, Kloss J, Ennis MJ, Armstrong BA, Loftus JC, Tran NL. Paulino VM, et al. Among authors: loftus jc. Mol Cancer Res. 2010 Nov;8(11):1558-67. doi: 10.1158/1541-7786.MCR-10-0334. Epub 2010 Sep 29. Mol Cancer Res. 2010. PMID: 20881009 Free PMC article.

5

Cdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cells.

Fortin SP, Ennis MJ, Schumacher CA, Zylstra-Diegel CR, Williams BO, Ross JT, Winkles JA, Loftus JC, Symons MH, Tran NL. Fortin SP, et al. Among authors: loftus jc. Mol Cancer Res. 2012 Jul;10(7):958-68. doi: 10.1158/1541-7786.MCR-11-0616. Epub 2012 May 9. Mol Cancer Res. 2012. PMID: 22571869 Free PMC article.

6

miRNA expression profiling in migrating glioblastoma cells: regulation of cell migration and invasion by miR-23b via targeting of Pyk2.

Loftus JC, Ross JT, Paquette KM, Paulino VM, Nasser S, Yang Z, Kloss J, Kim S, Berens ME, Tran NL. Loftus JC, et al. PLoS One. 2012;7(6):e39818. doi: 10.1371/journal.pone.0039818. Epub 2012 Jun 22. PLoS One. 2012. PMID: 22745829 Free PMC article.

7

TROY (TNFRSF19) promotes glioblastoma survival signaling and therapeutic resistance.

Loftus JC, Dhruv H, Tuncali S, Kloss J, Yang Z, Schumacher CA, Cao B, Williams BO, Eschbacher JM, Ross JT, Tran NL. Loftus JC, et al. Mol Cancer Res. 2013 Aug;11(8):865-74. doi: 10.1158/1541-7786.MCR-13-0008. Epub 2013 May 22. Mol Cancer Res. 2013. PMID: 23699535 Free PMC article.

8

The Src homology 3 domain-containing guanine nucleotide exchange factor is overexpressed in high-grade gliomas and promotes tumor necrosis factor-like weak inducer of apoptosis-fibroblast growth factor-inducible 14-induced cell migration and invasion via tumor necrosis factor receptor-associated factor 2.

Fortin Ensign SP, Mathews IT, Eschbacher JM, Loftus JC, Symons MH, Tran NL. Fortin Ensign SP, et al. Among authors: loftus jc. J Biol Chem. 2013 Jul 26;288(30):21887-97. doi: 10.1074/jbc.M113.468686. Epub 2013 Jun 17. J Biol Chem. 2013. PMID: 23775076 Free PMC article.

9

Propentofylline inhibits glioblastoma cell invasion and survival by targeting the TROY signaling pathway.

Dhruv HD, Roos A, Tomboc PJ, Tuncali S, Chavez A, Mathews I, Berens ME, Loftus JC, Tran NL. Dhruv HD, et al. Among authors: loftus jc. J Neurooncol. 2016 Feb;126(3):397-404. doi: 10.1007/s11060-015-1981-0. Epub 2015 Nov 12. J Neurooncol. 2016. PMID: 26559543 Free PMC article.

10

SGEF Is Regulated via TWEAK/Fn14/NF-κB Signaling and Promotes Survival by Modulation of the DNA Repair Response to Temozolomide.

Ensign SP, Roos A, Mathews IT, Dhruv HD, Tuncali S, Sarkaria JN, Symons MH, Loftus JC, Berens ME, Tran NL. Ensign SP, et al. Among authors: loftus jc. Mol Cancer Res. 2016 Mar;14(3):302-12. doi: 10.1158/1541-7786.MCR-15-0183. Epub 2016 Jan 13. Mol Cancer Res. 2016. PMID: 26764186 Free PMC article.

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