Platt F - Search Results

1

N-Butyl-l-deoxynojirimycin (l-NBDNJ): Synthesis of an Allosteric Enhancer of α-Glucosidase Activity for the Treatment of Pompe Disease.

D'Alonzo D, De Fenza M, Porto C, Iacono R, Huebecker M, Cobucci-Ponzano B, Priestman DA, Platt F, Parenti G, Moracci M, Palumbo G, Guaragna A. D'Alonzo D, et al. Among authors: platt f. J Med Chem. 2017 Dec 14;60(23):9462-9469. doi: 10.1021/acs.jmedchem.7b00646. Epub 2017 Nov 22. J Med Chem. 2017. PMID: 29112434

2

Imino sugar therapy for type 1 Gaucher disease.

Priestman DA, Platt FM, Dwek RA, Butters TD. Priestman DA, et al. Among authors: platt fm. Glycobiology. 2000 Nov;10(11):iv-vi. Glycobiology. 2000. PMID: 11221677 No abstract available.

3

Inhibition of substrate synthesis as a strategy for glycolipid lysosomal storage disease therapy.

Platt FM, Jeyakumar M, Andersson U, Priestman DA, Dwek RA, Butters TD, Cox TM, Lachmann RH, Hollak C, Aerts JM, Van Weely S, Hrebícek M, Moyses C, Gow I, Elstein D, Zimran A. Platt FM, et al. J Inherit Metab Dis. 2001 Apr;24(2):275-90. doi: 10.1023/a:1010335505357. J Inherit Metab Dis. 2001. PMID: 11405346 Review.

4

Increased glycosphingolipid levels in serum and aortae of apolipoprotein E gene knockout mice.

Garner B, Priestman DA, Stocker R, Harvey DJ, Butters TD, Platt FM. Garner B, et al. J Lipid Res. 2002 Feb;43(2):205-14. J Lipid Res. 2002. PMID: 11861662 Free article.

5

Analysis of fluorescently labeled glycosphingolipid-derived oligosaccharides following ceramide glycanase digestion and anthranilic acid labeling.

Neville DC, Coquard V, Priestman DA, te Vruchte DJ, Sillence DJ, Dwek RA, Platt FM, Butters TD. Neville DC, et al. Anal Biochem. 2004 Aug 15;331(2):275-82. doi: 10.1016/j.ab.2004.03.051. Anal Biochem. 2004. PMID: 15265733

6

Severe endothelial dysfunction in the aorta of a mouse model of Fabry disease; partial prevention by N-butyldeoxynojirimycin treatment.

Heare T, Alp NJ, Priestman DA, Kulkarni AB, Qasba P, Butters TD, Dwek RA, Clarke K, Channon KM, Platt FM. Heare T, et al. Among authors: platt fm. J Inherit Metab Dis. 2007 Feb;30(1):79-87. doi: 10.1007/s10545-006-0473-y. Epub 2006 Dec 25. J Inherit Metab Dis. 2007. PMID: 17189993

7

Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals.

Speak AO, Salio M, Neville DC, Fontaine J, Priestman DA, Platt N, Heare T, Butters TD, Dwek RA, Trottein F, Exley MA, Cerundolo V, Platt FM. Speak AO, et al. Among authors: platt fm, platt n. Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5971-6. doi: 10.1073/pnas.0607285104. Epub 2007 Mar 19. Proc Natl Acad Sci U S A. 2007. PMID: 17372214 Free PMC article.

8

Accumulation of glucosylceramide in murine testis, caused by inhibition of beta-glucosidase 2: implications for spermatogenesis.

Walden CM, Sandhoff R, Chuang CC, Yildiz Y, Butters TD, Dwek RA, Platt FM, van der Spoel AC. Walden CM, et al. J Biol Chem. 2007 Nov 9;282(45):32655-64. doi: 10.1074/jbc.M702387200. Epub 2007 Sep 11. J Biol Chem. 2007. PMID: 17848577 Free article.

9

N-butyldeoxynojirimycin causes weight loss as a result of appetite suppression in lean and obese mice.

Priestman DA, van der Spoel AC, Butters TD, Dwek RA, Platt FM. Priestman DA, et al. Among authors: platt fm. Diabetes Obes Metab. 2008 Feb;10(2):159-66. doi: 10.1111/j.1463-1326.2006.00701.x. Diabetes Obes Metab. 2008. PMID: 18190430

10

β-Glucosidase 2 (GBA2) activity and imino sugar pharmacology.

Ridley CM, Thur KE, Shanahan J, Thillaiappan NB, Shen A, Uhl K, Walden CM, Rahim AA, Waddington SN, Platt FM, van der Spoel AC. Ridley CM, et al. J Biol Chem. 2013 Sep 6;288(36):26052-26066. doi: 10.1074/jbc.M113.463562. Epub 2013 Jul 23. J Biol Chem. 2013. PMID: 23880767 Free PMC article.

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