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Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate.
J Med Chem. 2017 Dec 14;60(23):9617-9629. doi: 10.1021/acs.jmedchem.7b00974. Epub 2017 Nov 21.
J Med Chem. 2017.
PMID: 29111717
Lead development: validation and application of high throughput screening for determination of pharmacokinetic parameters for enzyme inhibitors.
Singh J, Soloweij J, Allen M, Killar L, Ator M.
Singh J, et al. Among authors: soloweij j.
Bioorg Med Chem. 1996 May;4(5):639-43. doi: 10.1016/0968-0896(96)00057-0.
Bioorg Med Chem. 1996.
PMID: 8804527
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