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Febuxostat ameliorates secondary progressive experimental autoimmune encephalomyelitis by restoring mitochondrial energy production in a GOT2-dependent manner.
Honorat JA, Nakatsuji Y, Shimizu M, Kinoshita M, Sumi-Akamaru H, Sasaki T, Takata K, Koda T, Namba A, Yamashita K, Sanda E, Sakaguchi M, Kumanogoh A, Shirakura T, Tamura M, Sakoda S, Mochizuki H, Okuno T. Honorat JA, et al. Among authors: mochizuki h. PLoS One. 2017 Nov 6;12(11):e0187215. doi: 10.1371/journal.pone.0187215. eCollection 2017. PLoS One. 2017. PMID: 29107957 Free PMC article.
RGMa modulates T cell responses and is involved in autoimmune encephalomyelitis.
Muramatsu R, Kubo T, Mori M, Nakamura Y, Fujita Y, Akutsu T, Okuno T, Taniguchi J, Kumanogoh A, Yoshida M, Mochizuki H, Kuwabara S, Yamashita T. Muramatsu R, et al. Among authors: mochizuki h. Nat Med. 2011 Apr;17(4):488-94. doi: 10.1038/nm.2321. Epub 2011 Mar 20. Nat Med. 2011. PMID: 21423182
Elevation of Sema4A implicates Th cell skewing and the efficacy of IFN-β therapy in multiple sclerosis.
Nakatsuji Y, Okuno T, Moriya M, Sugimoto T, Kinoshita M, Takamatsu H, Nojima S, Kimura T, Kang S, Ito D, Nakagawa Y, Toyofuku T, Takata K, Nakano M, Kubo M, Suzuki S, Matsui-Hasumi A, Uto-Konomi A, Ogata A, Mochizuki H, Sakoda S, Kumanogoh A. Nakatsuji Y, et al. Among authors: mochizuki h. J Immunol. 2012 May 15;188(10):4858-65. doi: 10.4049/jimmunol.1102023. Epub 2012 Apr 9. J Immunol. 2012. PMID: 22491253
Genetic and infectious profiles of Japanese multiple sclerosis patients.
Yoshimura S, Isobe N, Yonekawa T, Matsushita T, Masaki K, Sato S, Kawano Y, Yamamoto K, Kira J; South Japan Multiple Sclerosis Genetics Consortium. Yoshimura S, et al. PLoS One. 2012;7(11):e48592. doi: 10.1371/journal.pone.0048592. Epub 2012 Nov 9. PLoS One. 2012. PMID: 23152786 Free PMC article.
1,700 results