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General and Modular Strategy for Designing Potent, Selective, and Pharmacologically Compliant Inhibitors of Rhomboid Proteases.
Cell Chem Biol. 2017 Dec 21;24(12):1523-1536.e4. doi: 10.1016/j.chembiol.2017.09.007. Epub 2017 Oct 26.
Cell Chem Biol. 2017.
PMID: 29107700
Free PMC article.
Substrate binding and specificity of rhomboid intramembrane protease revealed by substrate-peptide complex structures.
Zoll S, Stanchev S, Began J, Skerle J, Lepšík M, Peclinovská L, Majer P, Strisovsky K.
Zoll S, et al. Among authors: skerle j.
EMBO J. 2014 Oct 16;33(20):2408-21. doi: 10.15252/embj.201489367. Epub 2014 Sep 12.
EMBO J. 2014.
PMID: 25216680
Free PMC article.
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Sensitive Versatile Fluorogenic Transmembrane Peptide Substrates for Rhomboid Intramembrane Proteases.
Tichá A, Stanchev S, Škerle J, Began J, Ingr M, Švehlová K, Polovinkin L, Růžička M, Bednárová L, Hadravová R, Poláchová E, Rampírová P, Březinová J, Kašička V, Majer P, Strisovsky K.
Tichá A, et al. Among authors: skerle j.
J Biol Chem. 2017 Feb 17;292(7):2703-2713. doi: 10.1074/jbc.M116.762849. Epub 2017 Jan 9.
J Biol Chem. 2017.
PMID: 28069810
Free PMC article.
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Membrane Protein Dimerization in Cell-Derived Lipid Membranes Measured by FRET with MC Simulations.
Škerle J, Humpolíčková J, Johnson N, Rampírová P, Poláchová E, Fliegl M, Dohnálek J, Suchánková A, Jakubec D, Strisovsky K.
Škerle J, et al.
Biophys J. 2020 Apr 21;118(8):1861-1875. doi: 10.1016/j.bpj.2020.03.011. Epub 2020 Mar 29.
Biophys J. 2020.
PMID: 32246901
Free PMC article.
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