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Targeting tumor cells based on Phosphodiesterase 3A expression.
Nazir M, Senkowski W, Nyberg F, Blom K, Edqvist PH, Jarvius M, Andersson C, Gustafsson MG, Nygren P, Larsson R, Fryknäs M. Nazir M, et al. Among authors: jarvius m. Exp Cell Res. 2017 Dec 15;361(2):308-315. doi: 10.1016/j.yexcr.2017.10.032. Epub 2017 Oct 26. Exp Cell Res. 2017. PMID: 29107068
High content screening for inhibitors of protein interactions and post-translational modifications in primary cells by proximity ligation.
Leuchowius KJ, Jarvius M, Wickström M, Rickardson L, Landegren U, Larsson R, Söderberg O, Fryknäs M, Jarvius J. Leuchowius KJ, et al. Among authors: jarvius m, jarvius j. Mol Cell Proteomics. 2010 Jan;9(1):178-83. doi: 10.1074/mcp.M900331-MCP200. Epub 2009 Oct 27. Mol Cell Proteomics. 2010. PMID: 19864249 Free PMC article.
Screening for phenotype selective activity in multidrug resistant cells identifies a novel tubulin active agent insensitive to common forms of cancer drug resistance.
Fryknäs M, Gullbo J, Wang X, Rickardson L, Jarvius M, Wickström M, Hassan S, Andersson C, Gustafsson M, Westman G, Nygren P, Linder S, Larsson R. Fryknäs M, et al. Among authors: jarvius m. BMC Cancer. 2013 Aug 6;13:374. doi: 10.1186/1471-2407-13-374. BMC Cancer. 2013. PMID: 23919498 Free PMC article.
AKN-028 induces cell cycle arrest, downregulation of Myc associated genes and dose dependent reduction of tyrosine kinase activity in acute myeloid leukemia.
Eriksson A, Kalushkova A, Jarvius M, Hilhorst R, Rickardson L, Kultima HG, de Wijn R, Hovestad L, Fryknäs M, Öberg F, Larsson R, Parrow V, Höglund M. Eriksson A, et al. Among authors: jarvius m. Biochem Pharmacol. 2014 Jan 15;87(2):284-91. doi: 10.1016/j.bcp.2013.10.022. Epub 2013 Nov 4. Biochem Pharmacol. 2014. PMID: 24200998 Free article. Clinical Trial.
Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition.
Segerman A, Niklasson M, Haglund C, Bergström T, Jarvius M, Xie Y, Westermark A, Sönmez D, Hermansson A, Kastemar M, Naimaie-Ali Z, Nyberg F, Berglund M, Sundström M, Hesselager G, Uhrbom L, Gustafsson M, Larsson R, Fryknäs M, Segerman B, Westermark B. Segerman A, et al. Among authors: jarvius m. Cell Rep. 2016 Dec 13;17(11):2994-3009. doi: 10.1016/j.celrep.2016.11.056. Cell Rep. 2016. PMID: 27974212 Free article.
Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin.
Jiang Y, Marinescu VD, Xie Y, Jarvius M, Maturi NP, Haglund C, Olofsson S, Lindberg N, Olofsson T, Leijonmarck C, Hesselager G, Alafuzoff I, Fryknäs M, Larsson R, Nelander S, Uhrbom L. Jiang Y, et al. Among authors: jarvius m. Cell Rep. 2017 Jan 24;18(4):977-990. doi: 10.1016/j.celrep.2017.01.003. Cell Rep. 2017. PMID: 28122246 Free article.
37 results