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Optimization of a series of heterocycles as survival motor neuron gene transcription enhancers.
Choi S, Calder AN, Miller EH, Anderson KP, Fiejtek DK, Rietz A, Li H, Cherry JJ, Quist KM, Xing X, Glicksman MA, Cuny GD, Lorson CL, Androphy EA, Hodgetts KJ. Choi S, et al. Among authors: li h. Bioorg Med Chem Lett. 2017 Dec 1;27(23):5144-5148. doi: 10.1016/j.bmcl.2017.10.066. Epub 2017 Oct 26. Bioorg Med Chem Lett. 2017. PMID: 29103974 Free PMC article.
Discovery of a Small Molecule Probe That Post-Translationally Stabilizes the Survival Motor Neuron Protein for the Treatment of Spinal Muscular Atrophy.
Rietz A, Li H, Quist KM, Cherry JJ, Lorson CL, Burnett BG, Kern NL, Calder AN, Fritsche M, Lusic H, Boaler PJ, Choi S, Xing X, Glicksman MA, Cuny GD, Androphy EJ, Hodgetts KJ. Rietz A, et al. Among authors: li h. J Med Chem. 2017 Jun 8;60(11):4594-4610. doi: 10.1021/acs.jmedchem.6b01885. Epub 2017 May 19. J Med Chem. 2017. PMID: 28481536 Free PMC article.
In vitro and in vivo effects of 2,4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS: Context-specific modulation of SMN transcript levels.
Cherry JJ, DiDonato CJ, Androphy EJ, Calo A, Potter K, Custer SK, Du S, Foley TL, Gopalsamy A, Reedich EJ, Gordo SM, Gordon W, Hosea N, Jones LH, Krizay DK, LaRosa G, Li H, Mathur S, Menard CA, Patel P, Ramos-Zayas R, Rietz A, Rong H, Zhang B, Tones MA. Cherry JJ, et al. Among authors: li h. PLoS One. 2017 Sep 25;12(9):e0185079. doi: 10.1371/journal.pone.0185079. eCollection 2017. PLoS One. 2017. PMID: 28945765 Free PMC article.
Altered mRNA Splicing in SMN-Depleted Motor Neuron-Like Cells.
Custer SK, Gilson TD, Li H, Todd AG, Astroski JW, Lin H, Liu Y, Androphy EJ. Custer SK, et al. Among authors: li h. PLoS One. 2016 Oct 13;11(10):e0163954. doi: 10.1371/journal.pone.0163954. eCollection 2016. PLoS One. 2016. PMID: 27736905 Free PMC article.
Rules for dissipationless topotronics.
Yan Q, Li H, Jiang H, Sun QF, Xie XC. Yan Q, et al. Among authors: li h. Sci Adv. 2024 Jun 7;10(23):eado4756. doi: 10.1126/sciadv.ado4756. Epub 2024 Jun 5. Sci Adv. 2024. PMID: 38838153
113,309 results
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