Sparagna GC - Search Results

1

Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induce Post-Translational Modifications of AKAP121, DRP1, and OPA1 That Promote Mitochondrial Fission.

Tsushima K, Bugger H, Wende AR, Soto J, Jenson GA, Tor AR, McGlauflin R, Kenny HC, Zhang Y, Souvenir R, Hu XX, Sloan CL, Pereira RO, Lira VA, Spitzer KW, Sharp TL, Shoghi KI, Sparagna GC, Rog-Zielinska EA, Kohl P, Khalimonchuk O, Schaffer JE, Abel ED. Tsushima K, et al. Among authors: sparagna gc. Circ Res. 2018 Jan 5;122(1):58-73. doi: 10.1161/CIRCRESAHA.117.311307. Epub 2017 Nov 1. Circ Res. 2018. PMID: 29092894 Free PMC article.

2

The role of calcium-independent phospholipase A2 in cardiolipin remodeling in the spontaneously hypertensive heart failure rat heart.

Zachman DK, Chicco AJ, McCune SA, Murphy RC, Moore RL, Sparagna GC. Zachman DK, et al. Among authors: sparagna gc. J Lipid Res. 2010 Mar;51(3):525-34. doi: 10.1194/jlr.M000646. Epub 2009 Sep 9. J Lipid Res. 2010. PMID: 19741254 Free PMC article.

3

Linoleate-Enrichment of Mitochondrial Cardiolipin Molecular Species Is Developmentally Regulated and a Determinant of Metabolic Phenotype.

Sparagna GC, Jonscher RL, Shuff SR, Phillips EK, Wilson CE, Woulfe KC, Garcia AM, Stauffer BL, Chatfield KC. Sparagna GC, et al. Biology (Basel). 2022 Dec 24;12(1):32. doi: 10.3390/biology12010032. Biology (Basel). 2022. PMID: 36671725 Free PMC article.

4

Resistance of young rat hepatic mitochondria to bile acid-induced permeability transition: potential role of alpha-tocopherol.

Gumpricht E, Devereaux MW, Dahl R, Soden JS, Sparagna GC, Leonard SW, Traber MG, Sokol RJ. Gumpricht E, et al. Among authors: sparagna gc. Pediatr Res. 2008 Nov;64(5):498-504. doi: 10.1203/PDR.0b013e3181841ee1. Pediatr Res. 2008. PMID: 18596569 Free PMC article.

5

Delta-6-desaturase links polyunsaturated fatty acid metabolism with phospholipid remodeling and disease progression in heart failure.

Le CH, Mulligan CM, Routh MA, Bouma GJ, Frye MA, Jeckel KM, Sparagna GC, Lynch JM, Moore RL, McCune SA, Bristow M, Zarini S, Murphy RC, Chicco AJ. Le CH, et al. Among authors: sparagna gc. Circ Heart Fail. 2014 Jan;7(1):172-83. doi: 10.1161/CIRCHEARTFAILURE.113.000744. Epub 2013 Nov 27. Circ Heart Fail. 2014. PMID: 24284026

6

Chronic Lactate Exposure Decreases Mitochondrial Function by Inhibition of Fatty Acid Uptake and Cardiolipin Alterations in Neonatal Rat Cardiomyocytes.

San-Millan I, Sparagna GC, Chapman HL, Warkins VL, Chatfield KC, Shuff SR, Martinez JL, Brooks GA. San-Millan I, et al. Among authors: sparagna gc. Front Nutr. 2022 Mar 4;9:809485. doi: 10.3389/fnut.2022.809485. eCollection 2022. Front Nutr. 2022. PMID: 35308271 Free PMC article.

7

Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart.

Mulligan CM, Sparagna GC, Le CH, De Mooy AB, Routh MA, Holmes MG, Hickson-Bick DL, Zarini S, Murphy RC, Xu FY, Hatch GM, McCune SA, Moore RL, Chicco AJ. Mulligan CM, et al. Among authors: sparagna gc. Cardiovasc Res. 2012 Jun 1;94(3):460-8. doi: 10.1093/cvr/cvs118. Epub 2012 Mar 12. Cardiovasc Res. 2012. PMID: 22411972 Free PMC article.

8

Docosahexaenoic acid lowers cardiac mitochondrial enzyme activity by replacing linoleic acid in the phospholipidome.

Sullivan EM, Pennington ER, Sparagna GC, Torres MJ, Neufer PD, Harris M, Washington J, Anderson EJ, Zeczycki TN, Brown DA, Shaikh SR. Sullivan EM, et al. Among authors: sparagna gc. J Biol Chem. 2018 Jan 12;293(2):466-483. doi: 10.1074/jbc.M117.812834. Epub 2017 Nov 21. J Biol Chem. 2018. PMID: 29162722 Free PMC article.

9

Cardiolipin deficiency elevates susceptibility to a lipotoxic hypertrophic cardiomyopathy.

Cole LK, Mejia EM, Sparagna GC, Vandel M, Xiang B, Han X, Dedousis N, Kaufman BA, Dolinsky VW, Hatch GM. Cole LK, et al. Among authors: sparagna gc. J Mol Cell Cardiol. 2020 Jul;144:24-34. doi: 10.1016/j.yjmcc.2020.05.001. Epub 2020 May 11. J Mol Cell Cardiol. 2020. PMID: 32418915

10

Altered cardiolipin metabolism is associated with cardiac mitochondrial dysfunction in pulmonary vascular remodeled perinatal rat pups.

Cole LK, Sparagna GC, Dolinsky VW, Hatch GM. Cole LK, et al. Among authors: sparagna gc. PLoS One. 2022 Feb 10;17(2):e0263520. doi: 10.1371/journal.pone.0263520. eCollection 2022. PLoS One. 2022. PMID: 35143544 Free PMC article.

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