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A Natural Benzofuran from the Patagonic Aleurodiscus vitellinus Fungus has Potent Neuroprotective Properties on a Cellular Model of Amyloid-β Peptide Toxicity.
González-Ramírez M, Gavilán J, Silva-Grecchi T, Cajas-Madriaga D, Triviño S, Becerra J, Saez-Orellana F, Pérez C, Fuentealba J. González-Ramírez M, et al. Among authors: silva grecchi t. J Alzheimers Dis. 2018;61(4):1463-1475. doi: 10.3233/JAD-170958. J Alzheimers Dis. 2018. PMID: 29376877
P2X receptor overexpression induced by soluble oligomers of amyloid beta peptide potentiates synaptic failure and neuronal dyshomeostasis in cellular models of Alzheimer's disease.
Sáez-Orellana F, Fuentes-Fuentes MC, Godoy PA, Silva-Grecchi T, Panes JD, Guzmán L, Yévenes GE, Gavilán J, Egan TM, Aguayo LG, Fuentealba J. Sáez-Orellana F, et al. Among authors: silva grecchi t. Neuropharmacology. 2018 Jan;128:366-378. doi: 10.1016/j.neuropharm.2017.10.027. Epub 2017 Oct 25. Neuropharmacology. 2018. PMID: 29079292 Free PMC article.
17 Oxo Sparteine and Lupanine, Obtained from Cytisus scoparius, Exert a Neuroprotection against Soluble Oligomers of Amyloid-β Toxicity by Nicotinic Acetylcholine Receptors.
Gavilan J, Mennickent D, Ramirez-Molina O, Triviño S, Perez C, Silva-Grecchi T, Godoy PA, Becerra J, Aguayo LG, Moraga-Cid G, Martin VS, Yevenes GE, Castro PA, Guzman L, Fuentealba J. Gavilan J, et al. Among authors: silva grecchi t. J Alzheimers Dis. 2019;67(1):343-356. doi: 10.3233/JAD-180945. J Alzheimers Dis. 2019. PMID: 30584148
Changes in PGC-1α/SIRT1 Signaling Impact on Mitochondrial Homeostasis in Amyloid-Beta Peptide Toxicity Model.
Panes JD, Godoy PA, Silva-Grecchi T, Celis MT, Ramirez-Molina O, Gavilan J, Muñoz-Montecino C, Castro PA, Moraga-Cid G, Yévenes GE, Guzmán L, Salisbury JL, Trushina E, Fuentealba J. Panes JD, et al. Among authors: silva grecchi t. Front Pharmacol. 2020 May 21;11:709. doi: 10.3389/fphar.2020.00709. eCollection 2020. Front Pharmacol. 2020. PMID: 32523530 Free PMC article.
Increased expression of mitochondrial sodium-coupled ascorbic acid transporter-2 (mitSVCT2) as a central feature in breast cancer.
Peña E, Roa FJ, Inostroza E, Sotomayor K, González M, Gutierrez-Castro FA, Maurin M, Sweet K, Labrousse C, Gatica M, Aylwin CF, Mendoza P, Maldonado M, Delgado C, Madariaga J, Panes J, Silva-Grecchi T, Concha II, Moraga-Cid G, Reyes AM, Muñoz-Montesino C, Vera JC, Rivas CI. Peña E, et al. Among authors: silva grecchi t. Free Radic Biol Med. 2019 May 1;135:283-292. doi: 10.1016/j.freeradbiomed.2019.03.015. Epub 2019 Mar 19. Free Radic Biol Med. 2019. PMID: 30902760
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