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Half-life extension using serum albumin-binding DARPin® domains.
Steiner D, Merz FW, Sonderegger I, Gulotti-Georgieva M, Villemagne D, Phillips DJ, Forrer P, Stumpp MT, Zitt C, Binz HK. Steiner D, et al. Among authors: binz hk. Protein Eng Des Sel. 2017 Sep 1;30(9):583-591. doi: 10.1093/protein/gzx022. Protein Eng Des Sel. 2017. PMID: 29088432
Beyond Antibodies: The DARPin® Drug Platform.
Stumpp MT, Dawson KM, Binz HK. Stumpp MT, et al. Among authors: binz hk. BioDrugs. 2020 Aug;34(4):423-433. doi: 10.1007/s40259-020-00429-8. BioDrugs. 2020. PMID: 32583318 Free PMC article. Review.
DARPins: a new generation of protein therapeutics.
Stumpp MT, Binz HK, Amstutz P. Stumpp MT, et al. Among authors: binz hk. Drug Discov Today. 2008 Aug;13(15-16):695-701. doi: 10.1016/j.drudis.2008.04.013. Epub 2008 Jul 11. Drug Discov Today. 2008. PMID: 18621567 Review.
The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants.
Rothenberger S, Hurdiss DL, Walser M, Malvezzi F, Mayor J, Ryter S, Moreno H, Liechti N, Bosshart A, Iss C, Calabro V, Cornelius A, Hospodarsch T, Neculcea A, Looser T, Schlegel A, Fontaine S, Villemagne D, Paladino M, Schiegg D, Mangold S, Reichen C, Radom F, Kaufmann Y, Schaible D, Schlegel I, Zitt C, Sigrist G, Straumann M, Wolter J, Comby M, Sacarcelik F, Drulyte I, Lyoo H, Wang C, Li W, Du W, Binz HK, Herrup R, Lusvarghi S, Neerukonda SN, Vassell R, Wang W, Adler JM, Eschke K, Nascimento M, Abdelgawad A, Gruber AD, Bushe J, Kershaw O, Knutson CG, Balavenkatraman KK, Ramanathan K, Wyler E, Teixeira Alves LG, Lewis S, Watson R, Haeuptle MA, Zürcher A, Dawson KM, Steiner D, Weiss CD, Amstutz P, van Kuppeveld FJM, Stumpp MT, Bosch BJ, Engler O, Trimpert J. Rothenberger S, et al. Among authors: binz hk. Nat Biotechnol. 2022 Dec;40(12):1845-1854. doi: 10.1038/s41587-022-01382-3. Epub 2022 Jul 21. Nat Biotechnol. 2022. PMID: 35864170 Free PMC article.
126 results