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Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor.
Bertini S, Chicca A, Gado F, Arena C, Nieri D, Digiacomo M, Saccomanni G, Zhao P, Abood ME, Macchia M, Gertsch J, Manera C. Bertini S, et al. Among authors: abood me. Bioorg Med Chem. 2017 Dec 15;25(24):6427-6434. doi: 10.1016/j.bmc.2017.10.015. Epub 2017 Oct 16. Bioorg Med Chem. 2017. PMID: 29079014 Free PMC article.
CB2-selective cannabinoid receptor ligands: synthesis, pharmacological evaluation, and molecular modeling investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides.
Lucchesi V, Hurst DP, Shore DM, Bertini S, Ehrmann BM, Allarà M, Lawrence L, Ligresti A, Minutolo F, Saccomanni G, Sharir H, Macchia M, Di Marzo V, Abood ME, Reggio PH, Manera C. Lucchesi V, et al. Among authors: abood me. J Med Chem. 2014 Nov 13;57(21):8777-91. doi: 10.1021/jm500807e. Epub 2014 Oct 15. J Med Chem. 2014. PMID: 25272206 Free PMC article.
Structure-activity relationships of benzothiazole GPR35 antagonists.
Abdalhameed MM, Zhao P, Hurst DP, Reggio PH, Abood ME, Croatt MP. Abdalhameed MM, et al. Among authors: abood me. Bioorg Med Chem Lett. 2017 Feb 1;27(3):612-615. doi: 10.1016/j.bmcl.2016.12.012. Epub 2016 Dec 5. Bioorg Med Chem Lett. 2017. PMID: 27989666 Free PMC article.
Allosteric Modulators: A Side Door.
Abood ME. Abood ME. J Med Chem. 2016 Jan 14;59(1):42-3. doi: 10.1021/acs.jmedchem.5b01824. Epub 2015 Dec 8. J Med Chem. 2016. PMID: 26645411
Application of Fluorine- and Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of Cannabinoid 1 Receptor Positive Allosteric Modulators.
Garai S, Kulkarni PM, Schaffer PC, Leo LM, Brandt AL, Zagzoog A, Black T, Lin X, Hurst DP, Janero DR, Abood ME, Zimmowitch A, Straiker A, Pertwee RG, Kelly M, Szczesniak AM, Denovan-Wright EM, Mackie K, Hohmann AG, Reggio PH, Laprairie RB, Thakur GA. Garai S, et al. Among authors: abood me. J Med Chem. 2020 Jan 23;63(2):542-568. doi: 10.1021/acs.jmedchem.9b01142. Epub 2020 Jan 3. J Med Chem. 2020. PMID: 31756109 Free PMC article.
133 results