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Comparison of Whole Body SOD1 Knockout with Muscle-Specific SOD1 Knockout Mice Reveals a Role for Nerve Redox Signaling in Regulation of Degenerative Pathways in Skeletal Muscle.
Sakellariou GK, McDonagh B, Porter H, Giakoumaki II, Earl KE, Nye GA, Vasilaki A, Brooks SV, Richardson A, Van Remmen H, McArdle A, Jackson MJ. Sakellariou GK, et al. Antioxid Redox Signal. 2018 Feb 1;28(4):275-295. doi: 10.1089/ars.2017.7249. Epub 2017 Dec 12. Antioxid Redox Signal. 2018. PMID: 29065712 Free PMC article.
Studies of mitochondrial and nonmitochondrial sources implicate nicotinamide adenine dinucleotide phosphate oxidase(s) in the increased skeletal muscle superoxide generation that occurs during contractile activity.
Sakellariou GK, Vasilaki A, Palomero J, Kayani A, Zibrik L, McArdle A, Jackson MJ. Sakellariou GK, et al. Antioxid Redox Signal. 2013 Feb 20;18(6):603-21. doi: 10.1089/ars.2012.4623. Epub 2012 Dec 6. Antioxid Redox Signal. 2013. PMID: 23050834 Free PMC article.
Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype.
Sataranatarajan K, Qaisar R, Davis C, Sakellariou GK, Vasilaki A, Zhang Y, Liu Y, Bhaskaran S, McArdle A, Jackson M, Brooks SV, Richardson A, Van Remmen H. Sataranatarajan K, et al. Among authors: sakellariou gk. Redox Biol. 2015 Aug;5:140-148. doi: 10.1016/j.redox.2015.04.005. Epub 2015 Apr 15. Redox Biol. 2015. PMID: 25917273 Free PMC article.
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