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Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation.
He W, Liu M, Huang P, Abdel-Mageed WM, Han J, Watrous JD, Nguyen DD, Wang W, Song F, Dai H, Zhang J, Quinn RJ, Grkovi T, Luo H, Zhang L, Liu X. He W, et al. Among authors: wang w. Synth Syst Biotechnol. 2016 Jul 1;1(3):187-194. doi: 10.1016/j.synbio.2016.05.002. eCollection 2016 Sep. Synth Syst Biotechnol. 2016. PMID: 29062942 Free PMC article.
Fungal biotransformation of tanshinone results in [4+2] cycloaddition with sorbicillinol: evidence for enzyme catalysis and increased antibacterial activity.
He W, Liu M, Li X, Zhang X, Abdel-Mageed WM, Li L, Wang W, Zhang J, Han J, Dai H, Quinn RJ, Liu HW, Luo H, Zhang L, Liu X. He W, et al. Among authors: wang w. Appl Microbiol Biotechnol. 2016 Oct;100(19):8349-57. doi: 10.1007/s00253-016-7488-6. Epub 2016 May 20. Appl Microbiol Biotechnol. 2016. PMID: 27198724
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