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Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.
Paulk NK, Pekrun K, Zhu E, Nygaard S, Li B, Xu J, Chu K, Leborgne C, Dane AP, Haft A, Zhang Y, Zhang F, Morton C, Valentine MB, Davidoff AM, Nathwani AC, Mingozzi F, Grompe M, Alexander IE, Lisowski L, Kay MA. Paulk NK, et al. Among authors: nygaard s. Mol Ther. 2018 Jan 3;26(1):289-303. doi: 10.1016/j.ymthe.2017.09.021. Epub 2017 Sep 25. Mol Ther. 2018. PMID: 29055620 Free PMC article.
A universal system to select gene-modified hepatocytes in vivo.
Nygaard S, Barzel A, Haft A, Major A, Finegold M, Kay MA, Grompe M. Nygaard S, et al. Sci Transl Med. 2016 Jun 8;8(342):342ra79. doi: 10.1126/scitranslmed.aad8166. Sci Transl Med. 2016. PMID: 27280686 Free PMC article.
AAV-Mediated CRISPR/Cas9 Gene Editing in Murine Phenylketonuria.
Richards DY, Winn SR, Dudley S, Nygaard S, Mighell TL, Grompe M, Harding CO. Richards DY, et al. Among authors: nygaard s. Mol Ther Methods Clin Dev. 2019 Dec 24;17:234-245. doi: 10.1016/j.omtm.2019.12.004. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2019. PMID: 31970201 Free PMC article.
Brain-derived neurotrophic factor activation of CaM-kinase kinase via transient receptor potential canonical channels induces the translation and synaptic incorporation of GluA1-containing calcium-permeable AMPA receptors.
Fortin DA, Srivastava T, Dwarakanath D, Pierre P, Nygaard S, Derkach VA, Soderling TR. Fortin DA, et al. Among authors: nygaard s. J Neurosci. 2012 Jun 13;32(24):8127-37. doi: 10.1523/JNEUROSCI.6034-11.2012. J Neurosci. 2012. PMID: 22699894 Free PMC article.
108 results