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89 results

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Targeting class I histone deacetylases by the novel small molecule inhibitor 4SC-202 blocks oncogenic hedgehog-GLI signaling and overcomes smoothened inhibitor resistance.
Gruber W, Peer E, Elmer DP, Sternberg C, Tesanovic S, Del Burgo P, Coni S, Canettieri G, Neureiter D, Bartz R, Kohlhof H, Vitt D, Aberger F. Gruber W, et al. Among authors: canettieri g. Int J Cancer. 2018 Mar 1;142(5):968-975. doi: 10.1002/ijc.31117. Epub 2017 Nov 6. Int J Cancer. 2018. PMID: 29055107 Free PMC article.
Opposite Effect of Thyroid Hormones on Oxidative Stress and on Mitochondrial Respiration in COVID-19 Patients.
De Vitis C, Capalbo C, Torsello A, Napoli C, Salvati V, Loffredo C, Blandino G, Piaggio G, Auciello FR, Pelliccia F, Salerno G, Simmaco M, Di Magno L, Canettieri G, Coluzzi F, Mancini R, Rocco M, Sciacchitano S. De Vitis C, et al. Among authors: canettieri g. Antioxidants (Basel). 2022 Oct 8;11(10):1998. doi: 10.3390/antiox11101998. Antioxidants (Basel). 2022. PMID: 36290721 Free PMC article.
An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma.
De Smaele E, Fragomeli C, Ferretti E, Pelloni M, Po A, Canettieri G, Coni S, Di Marcotullio L, Greco A, Moretti M, Di Rocco C, Pazzaglia S, Maroder M, Screpanti I, Giannini G, Gulino A. De Smaele E, et al. Among authors: canettieri g. Neoplasia. 2008 Jan;10(1):89-98. doi: 10.1593/neo.07891. Neoplasia. 2008. PMID: 18231642 Free PMC article.
The coactivator CRTC1 promotes cell proliferation and transformation via AP-1.
Canettieri G, Coni S, Della Guardia M, Nocerino V, Antonucci L, Di Magno L, Screaton R, Screpanti I, Giannini G, Gulino A. Canettieri G, et al. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1445-50. doi: 10.1073/pnas.0808749106. Epub 2009 Jan 21. Proc Natl Acad Sci U S A. 2009. PMID: 19164581 Free PMC article.
TORCs/CRTCs: more than mere coincidence.
Canettieri G, Coni S, Antonucci L, Di Magno L, Gulino A. Canettieri G, et al. Cell Cycle. 2009 Apr 1;8(7):963-4. Epub 2009 Apr 9. Cell Cycle. 2009. PMID: 19287208 No abstract available.
Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation.
Canettieri G, Di Marcotullio L, Greco A, Coni S, Antonucci L, Infante P, Pietrosanti L, De Smaele E, Ferretti E, Miele E, Pelloni M, De Simone G, Pedone EM, Gallinari P, Giorgi A, Steinkühler C, Vitagliano L, Pedone C, Schinin ME, Screpanti I, Gulino A. Canettieri G, et al. Nat Cell Biol. 2010 Feb;12(2):132-42. doi: 10.1038/ncb2013. Epub 2010 Jan 17. Nat Cell Biol. 2010. PMID: 20081843
Hedgehog controls neural stem cells through p53-independent regulation of Nanog.
Po A, Ferretti E, Miele E, De Smaele E, Paganelli A, Canettieri G, Coni S, Di Marcotullio L, Biffoni M, Massimi L, Di Rocco C, Screpanti I, Gulino A. Po A, et al. Among authors: canettieri g. EMBO J. 2010 Aug 4;29(15):2646-58. doi: 10.1038/emboj.2010.131. Epub 2010 Jun 25. EMBO J. 2010. PMID: 20581804 Free PMC article.
89 results