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HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33.
Osbourn M, Soares DC, Vacca F, Cohen ES, Scott IC, Gregory WF, Smyth DJ, Toivakka M, Kemter AM, le Bihan T, Wear M, Hoving D, Filbey KJ, Hewitson JP, Henderson H, Gonzàlez-Cìscar A, Errington C, Vermeren S, Astier AL, Wallace WA, Schwarze J, Ivens AC, Maizels RM, McSorley HJ. Osbourn M, et al. Among authors: soares dc. Immunity. 2017 Oct 17;47(4):739-751.e5. doi: 10.1016/j.immuni.2017.09.015. Immunity. 2017. PMID: 29045903 Free PMC article.
A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells.
Johnston CJC, Smyth DJ, Kodali RB, White MPJ, Harcus Y, Filbey KJ, Hewitson JP, Hinck CS, Ivens A, Kemter AM, Kildemoes AO, Le Bihan T, Soares DC, Anderton SM, Brenn T, Wigmore SJ, Woodcock HV, Chambers RC, Hinck AP, McSorley HJ, Maizels RM. Johnston CJC, et al. Among authors: soares dc. Nat Commun. 2017 Nov 23;8(1):1741. doi: 10.1038/s41467-017-01886-6. Nat Commun. 2017. PMID: 29170498 Free PMC article.
The mitosis and neurodevelopment proteins NDE1 and NDEL1 form dimers, tetramers, and polymers with a folded back structure in solution.
Soares DC, Bradshaw NJ, Zou J, Kennaway CK, Hamilton RS, Chen ZA, Wear MA, Blackburn EA, Bramham J, Böttcher B, Millar JK, Barlow PN, Walkinshaw MD, Rappsilber J, Porteous DJ. Soares DC, et al. J Biol Chem. 2012 Sep 21;287(39):32381-93. doi: 10.1074/jbc.M112.393439. Epub 2012 Jul 27. J Biol Chem. 2012. PMID: 22843697 Free PMC article.
A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins.
Eykelenboom JE, Briggs GJ, Bradshaw NJ, Soares DC, Ogawa F, Christie S, Malavasi EL, Makedonopoulou P, Mackie S, Malloy MP, Wear MA, Blackburn EA, Bramham J, McIntosh AM, Blackwood DH, Muir WJ, Porteous DJ, Millar JK. Eykelenboom JE, et al. Among authors: soares dc. Hum Mol Genet. 2012 Aug 1;21(15):3374-86. doi: 10.1093/hmg/dds169. Epub 2012 Apr 30. Hum Mol Genet. 2012. PMID: 22547224 Free PMC article.
The DISC locus in psychiatric illness.
Chubb JE, Bradshaw NJ, Soares DC, Porteous DJ, Millar JK. Chubb JE, et al. Among authors: soares dc. Mol Psychiatry. 2008 Jan;13(1):36-64. doi: 10.1038/sj.mp.4002106. Epub 2007 Oct 2. Mol Psychiatry. 2008. PMID: 17912248 Review.
134 results