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Fragment-derived modulators of an industrial β-glucosidase.
Makraki E, Darby JF, Carneiro MG, Firth JD, Heyam A, Ab E, O'Brien P, Siegal G, Hubbard RE. Makraki E, et al. Among authors: heyam a. Biochem J. 2020 Nov 27;477(22):4383-4395. doi: 10.1042/BCJ20200507. Biochem J. 2020. PMID: 33111951 Free PMC article.
Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides.
Keenan T, Parmeggiani F, Malassis J, Fontenelle CQ, Vendeville JB, Offen W, Both P, Huang K, Marchesi A, Heyam A, Young C, Charnock SJ, Davies GJ, Linclau B, Flitsch SL, Fascione MA. Keenan T, et al. Among authors: heyam a. Cell Chem Biol. 2020 Sep 17;27(9):1199-1206.e5. doi: 10.1016/j.chembiol.2020.06.005. Epub 2020 Jul 2. Cell Chem Biol. 2020. PMID: 32619452 Free article.
A Reductive Aminase Switches to Imine Reductase Mode for a Bulky Amine Substrate.
Gilio AK, Thorpe TW, Heyam A, Petchey MR, Pogrányi B, France SP, Howard RM, Karmilowicz MJ, Lewis R, Turner N, Grogan G. Gilio AK, et al. Among authors: heyam a. ACS Catal. 2023 Jan 12;13(3):1669-1677. doi: 10.1021/acscatal.2c06066. eCollection 2023 Feb 3. ACS Catal. 2023. PMID: 36776386 Free PMC article.
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