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Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells.
Carrington EM, Zhang JG, Sutherland RM, Vikstrom IB, Brady JL, Soo P, Vremec D, Allison C, Lee EF, Fairlie WD, Bouillet P, Grabow S, Ottina E, Herold MJ, Pellegrini M, Huang DC, Tarlinton DM, Strasser A, Lew AM, Zhan Y. Carrington EM, et al. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4044-9. doi: 10.1073/pnas.1417620112. Epub 2015 Mar 16. Proc Natl Acad Sci U S A. 2015. PMID: 25775525 Free PMC article.
Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment.
Schenk RL, Tuzlak S, Carrington EM, Zhan Y, Heinzel S, Teh CE, Gray DH, Tai L, Lew AM, Villunger A, Strasser A, Herold MJ. Schenk RL, et al. Among authors: carrington em. Cell Death Differ. 2017 Mar;24(3):534-545. doi: 10.1038/cdd.2016.156. Epub 2017 Jan 13. Cell Death Differ. 2017. PMID: 28085150 Free PMC article.
Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo.
Carrington EM, Zhan Y, Brady JL, Zhang JG, Sutherland RM, Anstee NS, Schenk RL, Vikstrom IB, Delconte RB, Segal D, Huntington ND, Bouillet P, Tarlinton DM, Huang DC, Strasser A, Cory S, Herold MJ, Lew AM. Carrington EM, et al. Cell Death Differ. 2017 May;24(5):878-888. doi: 10.1038/cdd.2017.30. Epub 2017 Mar 31. Cell Death Differ. 2017. PMID: 28362427 Free PMC article.
169 results