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Data demonstrating the role of peroxiredoxin 2 as important anti-oxidant system in lung homeostasis.
Federti E, Matte A, Ghigo A, Andolfo I, James C, Siciliano A, Leboeuf C, Janin A, Manna F, Choi SY, Iolascon A, Beneduce E, Melisi D, Kim DW, Levi S, De Franceschi L. Federti E, et al. Among authors: de franceschi l. Data Brief. 2017 Sep 30;15:376-381. doi: 10.1016/j.dib.2017.09.062. eCollection 2017 Dec. Data Brief. 2017. PMID: 29034295 Free PMC article.
Endothelin receptor antagonism prevents hypoxia-induced mortality and morbidity in a mouse model of sickle-cell disease.
Sabaa N, de Franceschi L, Bonnin P, Castier Y, Malpeli G, Debbabi H, Galaup A, Maier-Redelsperger M, Vandermeersch S, Scarpa A, Janin A, Levy B, Girot R, Beuzard Y, Leboeuf C, Henri A, Germain S, Dussaule JC, Tharaux PL. Sabaa N, et al. Among authors: de franceschi l. J Clin Invest. 2008 May;118(5):1924-33. doi: 10.1172/JCI33308. J Clin Invest. 2008. PMID: 18382768 Free PMC article.
Peroxiredoxin-2 expression is increased in beta-thalassemic mouse red cells but is displaced from the membrane as a marker of oxidative stress.
Matte A, Low PS, Turrini F, Bertoldi M, Campanella ME, Spano D, Pantaleo A, Siciliano A, De Franceschi L. Matte A, et al. Among authors: de franceschi l. Free Radic Biol Med. 2010 Aug 1;49(3):457-66. doi: 10.1016/j.freeradbiomed.2010.05.003. Epub 2010 May 19. Free Radic Biol Med. 2010. PMID: 20488244 Free PMC article.
Abnormal modulation of cell protective systems in response to ischemic/reperfusion injury is important in the development of mouse sickle cell hepatopathy.
Siciliano A, Malpeli G, Platt OS, Lebouef C, Janin A, Scarpa A, Olivieri O, Amato E, Corrocher R, Beuzard Y, De Franceschi L. Siciliano A, et al. Among authors: de franceschi l. Haematologica. 2011 Jan;96(1):24-32. doi: 10.3324/haematol.2010.028506. Epub 2010 Sep 17. Haematologica. 2011. PMID: 20851863 Free PMC article.
Oxidative stress modulates heme synthesis and induces peroxiredoxin-2 as a novel cytoprotective response in β-thalassemic erythropoiesis.
De Franceschi L, Bertoldi M, De Falco L, Santos Franco S, Ronzoni L, Turrini F, Colancecco A, Camaschella C, Cappellini MD, Iolascon A. De Franceschi L, et al. Among authors: de falco l. Haematologica. 2011 Nov;96(11):1595-604. doi: 10.3324/haematol.2011.043612. Epub 2011 Jul 12. Haematologica. 2011. PMID: 21750082 Free PMC article. Clinical Trial.
254 results