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Growth hormone secretagogues hexarelin and JMV2894 protect skeletal muscle from mitochondrial damages in a rat model of cisplatin-induced cachexia.
Sirago G, Conte E, Fracasso F, Cormio A, Fehrentz JA, Martinez J, Musicco C, Camerino GM, Fonzino A, Rizzi L, Torsello A, Lezza AMS, Liantonio A, Cantatore P, Pesce V. Sirago G, et al. Among authors: torsello a. Sci Rep. 2017 Oct 12;7(1):13017. doi: 10.1038/s41598-017-13504-y. Sci Rep. 2017. PMID: 29026190 Free PMC article.
New active series of growth hormone secretagogues.
Guerlavais V, Boeglin D, Mousseaux D, Oiry C, Heitz A, Deghenghi R, Locatelli V, Torsello A, Ghé C, Catapano F, Muccioli G, Galleyrand JC, Fehrentz JA, Martinez J. Guerlavais V, et al. Among authors: torsello a. J Med Chem. 2003 Mar 27;46(7):1191-203. doi: 10.1021/jm020985q. J Med Chem. 2003. PMID: 12646029
Toward potent ghrelin receptor ligands based on trisubstituted 1,2,4-triazole structure. 2. Synthesis and pharmacological in vitro and in vivo evaluations.
Moulin A, Demange L, Bergé G, Gagne D, Ryan J, Mousseaux D, Heitz A, Perrissoud D, Locatelli V, Torsello A, Galleyrand JC, Fehrentz JA, Martinez J. Moulin A, et al. Among authors: torsello a. J Med Chem. 2007 Nov 15;50(23):5790-806. doi: 10.1021/jm0704550. Epub 2007 Oct 10. J Med Chem. 2007. PMID: 17927165
New trisubstituted 1,2,4-triazole derivatives as potent ghrelin receptor antagonists. 3. Synthesis and pharmacological in vitro and in vivo evaluations.
Moulin A, Demange L, Ryan J, Mousseaux D, Sanchez P, Bergé G, Gagne D, Perrissoud D, Locatelli V, Torsello A, Galleyrand JC, Fehrentz JA, Martinez J. Moulin A, et al. Among authors: torsello a. J Med Chem. 2008 Feb 14;51(3):689-93. doi: 10.1021/jm701292s. Epub 2008 Jan 15. J Med Chem. 2008. PMID: 18193826
Biophysical characterization of a binding site for TLQP-21, a naturally occurring peptide which induces resistance to obesity.
Cassina V, Torsello A, Tempestini A, Salerno D, Brogioli D, Tamiazzo L, Bresciani E, Martinez J, Fehrentz JA, Verdié P, Omeljaniuk RJ, Possenti R, Rizzi L, Locatelli V, Mantegazza F. Cassina V, et al. Among authors: torsello a. Biochim Biophys Acta. 2013 Feb;1828(2):455-60. doi: 10.1016/j.bbamem.2012.10.023. Epub 2012 Oct 30. Biochim Biophys Acta. 2013. PMID: 23122777 Free article.
171 results