Xin Y - Search Results

1

The Relative Bioavailability, Food Effect, and Drug Interaction With Omeprazole of Momelotinib Tablet Formulation in Healthy Subjects.

Xin Y, Shao L, Maltzman J, Stefanidis D, Hemenway J, Tarnowski T, Deng W, Silverman JA. Xin Y, et al. Clin Pharmacol Drug Dev. 2018 Mar;7(3):277-286. doi: 10.1002/cpdd.397. Epub 2017 Oct 11. Clin Pharmacol Drug Dev. 2018. PMID: 29024542 Clinical Trial.

2

The Drug-Drug Interaction Profile of Presatovir.

Xin Y, Weng W, Murray BP, Eisenberg EJ, Chien JW, Ling J, Silverman JA. Xin Y, et al. J Clin Pharmacol. 2018 Jun;58(6):771-780. doi: 10.1002/jcph.1073. Epub 2018 Feb 7. J Clin Pharmacol. 2018. PMID: 29412463 Clinical Trial.

3

Pharmacokinetics and Safety of Momelotinib in Subjects With Hepatic or Renal Impairment.

Xin Y, Kawashima J, Weng W, Kwan E, Tarnowski T, Silverman JA. Xin Y, et al. J Clin Pharmacol. 2018 Apr;58(4):522-532. doi: 10.1002/jcph.1050. Epub 2017 Dec 28. J Clin Pharmacol. 2018. PMID: 29283448 Clinical Trial.

4

Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite-Resolution for Clinical Development.

Zheng J, Xin Y, Zhang J, Subramanian R, Murray BP, Whitney JA, Warr MR, Ling J, Moorehead L, Kwan E, Hemenway J, Smith BJ, Silverman JA. Zheng J, et al. Among authors: xin y. Drug Metab Dispos. 2018 Mar;46(3):237-247. doi: 10.1124/dmd.117.078899. Epub 2018 Jan 8. Drug Metab Dispos. 2018. PMID: 29311136

5

The Relative Bioavailability and Effects of Food and Acid-Reducing Agents on Filgotinib Tablets in Healthy Subjects.

Anderson K, Zheng H, Kotecha M, Cuvin J, Scott B, Sharma S, Qin AR, Namour F, Xin Y. Anderson K, et al. Among authors: xin y. Clin Pharmacol Drug Dev. 2019 Jul;8(5):585-594. doi: 10.1002/cpdd.659. Epub 2019 Feb 15. Clin Pharmacol Drug Dev. 2019. PMID: 30768860 Clinical Trial.

6

A phase 2 study of momelotinib, a potent JAK1 and JAK2 inhibitor, in patients with polycythemia vera or essential thrombocythemia.

Verstovsek S, Courby S, Griesshammer M, Mesa RA, Brachmann CB, Kawashima J, Maltzman JD, Shao L, Xin Y, Huang D, Bajel A. Verstovsek S, et al. Among authors: xin y. Leuk Res. 2017 Sep;60:11-17. doi: 10.1016/j.leukres.2017.05.002. Epub 2017 May 30. Leuk Res. 2017. PMID: 28622623 Free PMC article. Clinical Trial.

7

Filgotinib, a JAK1 Inhibitor, Has No Effect on QT Interval in Healthy Subjects.

Anderson K, Xin Y, Zheng H, Yun C, Kwan E, Qin A, Namour F, Kearney BP, Mathias A. Anderson K, et al. Among authors: xin y. Clin Pharmacol Drug Dev. 2020 Jan;9(1):32-40. doi: 10.1002/cpdd.755. Epub 2019 Dec 2. Clin Pharmacol Drug Dev. 2020. PMID: 31797578 Clinical Trial.

8

Randomised clinical trial: a phase 1, dose-ranging study of the anti-matrix metalloproteinase-9 monoclonal antibody GS-5745 versus placebo for ulcerative colitis.

Sandborn WJ, Bhandari BR, Fogel R, Onken J, Yen E, Zhao X, Jiang Z, Ge D, Xin Y, Ye Z, French D, Silverman JA, Kanwar B, Subramanian GM, McHutchison JG, Lee SD, Shackelton LM, Pai RK, Levesque BG, Feagan BG. Sandborn WJ, et al. Among authors: xin y. Aliment Pharmacol Ther. 2016 Jul;44(2):157-69. doi: 10.1111/apt.13653. Epub 2016 May 24. Aliment Pharmacol Ther. 2016. PMID: 27218676 Free PMC article. Clinical Trial.

9

Phase 1 First-in-Human, Single- and Multiple-Ascending Dose, and Food Effect Studies to Assess the Safety, Tolerability, and Pharmacokinetics of Presatovir for the Treatment of Respiratory Syncytial Virus Infection.

German P, Xin Y, Chien JW, Weng W, Mackman R, Lewis SA, Meng A, Ling J, Mathias A. German P, et al. Among authors: xin y. J Clin Pharmacol. 2018 Aug;58(8):1025-1034. doi: 10.1002/jcph.1112. Epub 2018 Apr 17. J Clin Pharmacol. 2018. PMID: 29663420

10

A phase 1/2, open-label study evaluating twice-daily administration of momelotinib in myelofibrosis.

Gupta V, Mesa RA, Deininger MW, Rivera CE, Sirhan S, Brachmann CB, Collins H, Kawashima J, Xin Y, Verstovsek S. Gupta V, et al. Among authors: xin y. Haematologica. 2017 Jan;102(1):94-102. doi: 10.3324/haematol.2016.148924. Epub 2016 Sep 15. Haematologica. 2017. PMID: 27634203 Free PMC article. Clinical Trial.

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