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Page 1
Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines.
France SP, Aleku GA, Sharma M, Mangas-Sanchez J, Howard RM, Steflik J, Kumar R, Adams RW, Slabu I, Crook R, Grogan G, Wallace TW, Turner NJ. France SP, et al. Angew Chem Int Ed Engl. 2017 Dec 4;56(49):15589-15593. doi: 10.1002/anie.201708453. Epub 2017 Nov 7. Angew Chem Int Ed Engl. 2017. PMID: 29024400 Free article.
Imine reductases (IREDs).
Mangas-Sanchez J, France SP, Montgomery SL, Aleku GA, Man H, Sharma M, Ramsden JI, Grogan G, Turner NJ. Mangas-Sanchez J, et al. Among authors: france sp. Curr Opin Chem Biol. 2017 Apr;37:19-25. doi: 10.1016/j.cbpa.2016.11.022. Epub 2016 Dec 27. Curr Opin Chem Biol. 2017. PMID: 28038349 Free article. Review.
A reductive aminase from Aspergillus oryzae.
Aleku GA, France SP, Man H, Mangas-Sanchez J, Montgomery SL, Sharma M, Leipold F, Hussain S, Grogan G, Turner NJ. Aleku GA, et al. Among authors: france sp. Nat Chem. 2017 Oct;9(10):961-969. doi: 10.1038/nchem.2782. Epub 2017 May 29. Nat Chem. 2017. PMID: 28937665
Carboxylic acid reductases (CARs): An industrial perspective.
Derrington SR, Turner NJ, France SP. Derrington SR, et al. Among authors: france sp. J Biotechnol. 2019 Oct 10;304:78-88. doi: 10.1016/j.jbiotec.2019.08.010. Epub 2019 Aug 17. J Biotechnol. 2019. PMID: 31430498 Review.
A Reductive Aminase Switches to Imine Reductase Mode for a Bulky Amine Substrate.
Gilio AK, Thorpe TW, Heyam A, Petchey MR, Pogrányi B, France SP, Howard RM, Karmilowicz MJ, Lewis R, Turner N, Grogan G. Gilio AK, et al. Among authors: france sp. ACS Catal. 2023 Jan 12;13(3):1669-1677. doi: 10.1021/acscatal.2c06066. eCollection 2023 Feb 3. ACS Catal. 2023. PMID: 36776386 Free PMC article.
PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease.
Gopalsamy A, Aulabaugh AE, Barakat A, Beaumont KC, Cabral S, Canterbury DP, Casimiro-Garcia A, Chang JS, Chen MZ, Choi C, Dow RL, Fadeyi OO, Feng X, France SP, Howard RM, Janz JM, Jasti J, Jasuja R, Jones LH, King-Ahmad A, Knee KM, Kohrt JT, Limberakis C, Liras S, Martinez CA, McClure KF, Narayanan A, Narula J, Novak JJ, O'Connell TN, Parikh MD, Piotrowski DW, Plotnikova O, Robinson RP, Sahasrabudhe PV, Sharma R, Thuma BA, Vasa D, Wei L, Wenzel AZ, Withka JM, Xiao J, Yayla HG. Gopalsamy A, et al. Among authors: france sp. J Med Chem. 2021 Jan 14;64(1):326-342. doi: 10.1021/acs.jmedchem.0c01518. Epub 2020 Dec 24. J Med Chem. 2021. PMID: 33356244
Synthetic Approaches to the New Drugs Approved During 2020.
Flick AC, Leverett CA, Ding HX, McInturff EL, Fink SJ, Mahapatra S, Carney DW, Lindsey EA, DeForest JC, France SP, Berritt S, Bigi-Botterill SV, Gibson TS, Watson RB, Liu Y, O'Donnell CJ. Flick AC, et al. Among authors: france sp. J Med Chem. 2022 Jul 28;65(14):9607-9661. doi: 10.1021/acs.jmedchem.2c00710. Epub 2022 Jul 14. J Med Chem. 2022. PMID: 35833579 Review.
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