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NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency.
Matlock AD, Vaibhav V, Holewinski R, Venkatraman V, Dardov V, Manalo DM, Shelley B, Ornelas L, Banuelos M, Mandefro B, Escalante-Chong R, Li J, Finkbeiner S, Fraenkel E, Rothstein J, Thompson L, Sareen D, Svendsen CN; NIH NeuroLINCS Consortium; Van Eyk JE. Matlock AD, et al. Among authors: fraenkel e. Sci Data. 2023 Jan 11;10(1):24. doi: 10.1038/s41597-022-01687-7. Sci Data. 2023. PMID: 36631473 Free PMC article.
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.
Lim RG, Al-Dalahmah O, Wu J, Gold MP, Reidling JC, Tang G, Adam M, Dansu DK, Park HJ, Casaccia P, Miramontes R, Reyes-Ortiz AM, Lau A, Hickman RA, Khan F, Paryani F, Tang A, Ofori K, Miyoshi E, Michael N, McClure N, Flowers XE, Vonsattel JP, Davidson S, Menon V, Swarup V, Fraenkel E, Goldman JE, Thompson LM. Lim RG, et al. Among authors: fraenkel e. Nat Commun. 2022 Dec 21;13(1):7791. doi: 10.1038/s41467-022-35388-x. Nat Commun. 2022. PMID: 36543778 Free PMC article.
SAMNetWeb: identifying condition-specific networks linking signaling and transcription.
Gosline SJ, Oh C, Fraenkel E. Gosline SJ, et al. Among authors: fraenkel e. Bioinformatics. 2015 Apr 1;31(7):1124-6. doi: 10.1093/bioinformatics/btu748. Epub 2014 Nov 19. Bioinformatics. 2015. PMID: 25414365 Free PMC article.
These tools are primarily designed to analyse data from a single experiment (e.g. drug treatment versus control), creating a need for computational algorithms that can handle heterogeneous datasets across multiple experimental conditions at once. ...AVAILABILITY AND IMPLEM …
These tools are primarily designed to analyse data from a single experiment (e.g. drug treatment versus control), creating a need for …
149 results