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Brachyury-YAP Regulatory Axis Drives Stemness and Growth in Cancer.
Shah SR, David JM, Tippens ND, Mohyeldin A, Martinez-Gutierrez JC, Ganaha S, Schiapparelli P, Hamilton DH, Palena C, Levchenko A, Quiñones-Hinojosa A. Shah SR, et al. Among authors: levchenko a. Cell Rep. 2017 Oct 10;21(2):495-507. doi: 10.1016/j.celrep.2017.09.057. Cell Rep. 2017. PMID: 29020634 Free PMC article.
Mesenchymal stem cells from human fat engineered to secrete BMP4 are nononcogenic, suppress brain cancer, and prolong survival.
Li Q, Wijesekera O, Salas SJ, Wang JY, Zhu M, Aprhys C, Chaichana KL, Chesler DA, Zhang H, Smith CL, Guerrero-Cazares H, Levchenko A, Quinones-Hinojosa A. Li Q, et al. Among authors: levchenko a. Clin Cancer Res. 2014 May 1;20(9):2375-87. doi: 10.1158/1078-0432.CCR-13-1415. Clin Cancer Res. 2014. PMID: 24789034 Free PMC article.
Glucose-6-phosphatase is a key metabolic regulator of glioblastoma invasion.
Abbadi S, Rodarte JJ, Abutaleb A, Lavell E, Smith CL, Ruff W, Schiller J, Olivi A, Levchenko A, Guerrero-Cazares H, Quinones-Hinojosa A. Abbadi S, et al. Among authors: levchenko a. Mol Cancer Res. 2014 Nov;12(11):1547-59. doi: 10.1158/1541-7786.MCR-14-0106-T. Epub 2014 Jul 7. Mol Cancer Res. 2014. PMID: 25001192 Free PMC article.
Hypoxia-cultured human adipose-derived mesenchymal stem cells are non-oncogenic and have enhanced viability, motility, and tropism to brain cancer.
Feng Y, Zhu M, Dangelmajer S, Lee YM, Wijesekera O, Castellanos CX, Denduluri A, Chaichana KL, Li Q, Zhang H, Levchenko A, Guerrero-Cazares H, Quiñones-Hinojosa A. Feng Y, et al. Among authors: levchenko a. Cell Death Dis. 2014 Dec 11;5(12):e1567. doi: 10.1038/cddis.2014.521. Cell Death Dis. 2014. PMID: 25501828 Free PMC article.
Pre-exposure of human adipose mesenchymal stem cells to soluble factors enhances their homing to brain cancer.
Smith CL, Chaichana KL, Lee YM, Lin B, Stanko KM, O'Donnell T, Gupta S, Shah SR, Wang J, Wijesekera O, Delannoy M, Levchenko A, Quiñones-Hinojosa A. Smith CL, et al. Among authors: levchenko a. Stem Cells Transl Med. 2015 Mar;4(3):239-51. doi: 10.5966/sctm.2014-0149. Epub 2015 Feb 2. Stem Cells Transl Med. 2015. PMID: 25646527 Free PMC article.
Migration Phenotype of Brain-Cancer Cells Predicts Patient Outcomes.
Smith CL, Kilic O, Schiapparelli P, Guerrero-Cazares H, Kim DH, Sedora-Roman NI, Gupta S, O'Donnell T, Chaichana KL, Rodriguez FJ, Abbadi S, Park J, Quiñones-Hinojosa A, Levchenko A. Smith CL, et al. Among authors: levchenko a. Cell Rep. 2016 Jun 21;15(12):2616-24. doi: 10.1016/j.celrep.2016.05.042. Epub 2016 Jun 9. Cell Rep. 2016. PMID: 27292647 Free PMC article.
311 results