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Model-Informed Drug Development for Malaria Therapeutics.
Andrews KA, Wesche D, McCarthy J, Möhrle JJ, Tarning J, Phillips L, Kern S, Grasela T. Andrews KA, et al. Among authors: wesche d. Annu Rev Pharmacol Toxicol. 2018 Jan 6;58:567-582. doi: 10.1146/annurev-pharmtox-010715-103429. Epub 2017 Oct 6. Annu Rev Pharmacol Toxicol. 2018. PMID: 28992431 Free PMC article. Review.
Retrospective Analysis Using Pharmacokinetic/Pharmacodynamic Modeling and Simulation Offers Improvements in Efficiency of the Design of Volunteer Infection Studies for Antimalarial Drug Development.
Andrews KA, Owen JS, McCarthy J, Wesche D, Gobeau N, Grasela TH, Möhrle JJ. Andrews KA, et al. Among authors: wesche d. Clin Transl Sci. 2021 Mar;14(2):712-719. doi: 10.1111/cts.12934. Epub 2020 Dec 16. Clin Transl Sci. 2021. PMID: 33326705 Free PMC article.
Model-Informed Drug Development for Anti-Infectives: State of the Art and Future.
Rayner CR, Smith PF, Andes D, Andrews K, Derendorf H, Friberg LE, Hanna D, Lepak A, Mills E, Polasek TM, Roberts JA, Schuck V, Shelton MJ, Wesche D, Rowland-Yeo K. Rayner CR, et al. Among authors: wesche d. Clin Pharmacol Ther. 2021 Apr;109(4):867-891. doi: 10.1002/cpt.2198. Epub 2021 Mar 9. Clin Pharmacol Ther. 2021. PMID: 33555032 Free PMC article. Review.
Factors affecting the electrocardiographic QT interval in malaria: A systematic review and meta-analysis of individual patient data.
Chan XHS, Win YN, Haeusler IL, Tan JY, Loganathan S, Saralamba S, Chan SKS, Ashley EA, Barnes KI, Baiden R, Bassi PU, Djimde A, Dorsey G, Duparc S, Hanboonkunupakarn B, Ter Kuile FO, Lacerda MVG, Nasa A, Nosten FH, Onyeji CO, Pukrittayakamee S, Siqueira AM, Tarning J, Taylor WRJ, Valentini G, van Vugt M, Wesche D, Day NPJ, Huang CL, Brugada J, Price RN, White NJ. Chan XHS, et al. Among authors: wesche d. PLoS Med. 2020 Mar 5;17(3):e1003040. doi: 10.1371/journal.pmed.1003040. eCollection 2020 Mar. PLoS Med. 2020. PMID: 32134952 Free PMC article.
Association of Impaired Cytochrome P450 2D6 Activity Genotype and Phenotype With Therapeutic Efficacy of Primaquine Treatment for Latent Plasmodium vivax Malaria.
Baird JK, Louisa M, Noviyanti R, Ekawati L, Elyazar I, Subekti D, Chand K, Gayatri A, Instiaty, Soebianto S, Crenna-Darusallam C, Djoko D, Hasto BD, Meriyenes D, Wesche D, Nelwan EJ, Sutanto I, Sudoyo H, Setiabudy R. Baird JK, et al. Among authors: wesche d. JAMA Netw Open. 2018 Aug 3;1(4):e181449. doi: 10.1001/jamanetworkopen.2018.1449. JAMA Netw Open. 2018. PMID: 30646129 Free PMC article.
Liver-targeted polymeric prodrugs of 8-aminoquinolines for malaria radical cure.
Srinivasan S, Roy D, Chavas TEJ, Vlaskin V, Ho DK, Pottenger A, LeGuyader CLM, Maktabi M, Strauch P, Jackson C, Flaherty SM, Lin H, Zhang J, Pybus B, Li Q, Huber HE, Burke PA, Wesche D, Rochford R, Stayton PS. Srinivasan S, et al. Among authors: wesche d. J Control Release. 2021 Mar 10;331:213-227. doi: 10.1016/j.jconrel.2020.12.046. Epub 2020 Dec 27. J Control Release. 2021. PMID: 33378692
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