Ganson NJ - Search Results

1

A brush-polymer conjugate of exendin-4 reduces blood glucose for up to five days and eliminates poly(ethylene glycol) antigenicity.

Qi Y, Simakova A, Ganson NJ, Li X, Luginbuhl KM, Özer I, Liu W, Hershfield MS, Matyjaszewski K, Chilkoti A. Qi Y, et al. Among authors: ganson nj. Nat Biomed Eng. 2016;1:0002. doi: 10.1038/s41551-016-0002. Epub 2016 Nov 28. Nat Biomed Eng. 2016. PMID: 28989813 Free PMC article.

2

Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase.

Ganson NJ, Kelly SJ, Scarlett E, Sundy JS, Hershfield MS. Ganson NJ, et al. Arthritis Res Ther. 2006;8(1):R12. doi: 10.1186/ar1861. Arthritis Res Ther. 2006. PMID: 16356199 Free PMC article. Clinical Trial.

3

Architectural Modification of Conformal PEG-Bottlebrush Coatings Minimizes Anti-PEG Antigenicity While Preserving Stealth Properties.

Joh DY, Zimmers Z, Avlani M, Heggestad JT, Aydin HB, Ganson N, Kumar S, Fontes CM, Achar RK, Hershfield MS, Hucknall AM, Chilkoti A. Joh DY, et al. Adv Healthc Mater. 2019 Apr;8(8):e1801177. doi: 10.1002/adhm.201801177. Epub 2019 Mar 25. Adv Healthc Mater. 2019. PMID: 30908902 Free PMC article.

4

Pharmacokinetics and pharmacodynamics of intravenous PEGylated recombinant mammalian urate oxidase in patients with refractory gout.

Sundy JS, Ganson NJ, Kelly SJ, Scarlett EL, Rehrig CD, Huang W, Hershfield MS. Sundy JS, et al. Among authors: ganson nj. Arthritis Rheum. 2007 Mar;56(3):1021-8. doi: 10.1002/art.22403. Arthritis Rheum. 2007. PMID: 17328081 Free article. Clinical Trial.

5

Deficiency of Adenosine Deaminase 2 (DADA2), an Inherited Cause of Polyarteritis Nodosa and a Mimic of Other Systemic Rheumatologic Disorders.

Hashem H, Kelly SJ, Ganson NJ, Hershfield MS. Hashem H, et al. Among authors: ganson nj. Curr Rheumatol Rep. 2017 Oct 5;19(11):70. doi: 10.1007/s11926-017-0699-8. Curr Rheumatol Rep. 2017. PMID: 28983775 Review.

6

Anti-PEG Antibodies Inhibit the Anticoagulant Activity of PEGylated Aptamers.

Moreno A, Pitoc GA, Ganson NJ, Layzer JM, Hershfield MS, Tarantal AF, Sullenger BA. Moreno A, et al. Among authors: ganson nj. Cell Chem Biol. 2019 May 16;26(5):634-644.e3. doi: 10.1016/j.chembiol.2019.02.001. Epub 2019 Feb 28. Cell Chem Biol. 2019. PMID: 30827937 Free PMC article.

7

Pre-existing anti-polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer.

Ganson NJ, Povsic TJ, Sullenger BA, Alexander JH, Zelenkofske SL, Sailstad JM, Rusconi CP, Hershfield MS. Ganson NJ, et al. J Allergy Clin Immunol. 2016 May;137(5):1610-1613.e7. doi: 10.1016/j.jaci.2015.10.034. Epub 2015 Dec 11. J Allergy Clin Immunol. 2016. PMID: 26688515 Free PMC article. No abstract available.

8

Treating gout with pegloticase, a PEGylated urate oxidase, provides insight into the importance of uric acid as an antioxidant in vivo.

Hershfield MS, Roberts LJ 2nd, Ganson NJ, Kelly SJ, Santisteban I, Scarlett E, Jaggers D, Sundy JS. Hershfield MS, et al. Among authors: ganson nj. Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14351-6. doi: 10.1073/pnas.1001072107. Epub 2010 Jul 26. Proc Natl Acad Sci U S A. 2010. PMID: 20660758 Free PMC article.

9

Adenosine deaminase type 2 deficiency masquerading as GATA2 deficiency: Successful hematopoietic stem cell transplantation.

Hsu AP, West RR, Calvo KR, Cuellar-Rodriguez J, Parta M, Kelly SJ, Ganson NJ, Hershfield MS, Holland SM, Hickstein DD. Hsu AP, et al. Among authors: ganson nj. J Allergy Clin Immunol. 2016 Aug;138(2):628-630.e2. doi: 10.1016/j.jaci.2016.03.016. Epub 2016 Apr 6. J Allergy Clin Immunol. 2016. PMID: 27130863 Free PMC article. No abstract available.

10

Hematopoietic stem cell transplantation rescues the immunologic phenotype and prevents vasculopathy in patients with adenosine deaminase 2 deficiency.

Van Eyck L Jr, Hershfield MS, Pombal D, Kelly SJ, Ganson NJ, Moens L, Frans G, Schaballie H, De Hertogh G, Dooley J, Bossuyt X, Wouters C, Liston A, Meyts I. Van Eyck L Jr, et al. Among authors: ganson nj. J Allergy Clin Immunol. 2015 Jan;135(1):283-7.e5. doi: 10.1016/j.jaci.2014.10.010. Epub 2014 Nov 25. J Allergy Clin Immunol. 2015. PMID: 25457153 Free PMC article. No abstract available.

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