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Genetic risk factors for pediatric-onset multiple sclerosis.
Gianfrancesco MA, Stridh P, Shao X, Rhead B, Graves JS, Chitnis T, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Mar S, Kahn I, Rose J, Roalstad S, Casper TC, Shen L, Quach H, Quach D, Hillert J, Hedstrom A, Olsson T, Kockum I, Alfredsson L, Schaefer C, Barcellos LF, Waubant E; Network of Pediatric Multiple Sclerosis Centers. Gianfrancesco MA, et al. Among authors: kockum i. Mult Scler. 2018 Dec;24(14):1825-1834. doi: 10.1177/1352458517733551. Epub 2017 Oct 5. Mult Scler. 2018. PMID: 28980494 Free PMC article.
D6S265*15 marks a DRB1*15, DQB1*0602 haplotype associated with attenuated protection from type 1 diabetes mellitus.
Valdes AM, Thomson G, Graham J, Zarghami M, McNeney B, Kockum I, Smith A, Lathrop M, Steenkiste AR, Dorman JS, Noble JA, Hansen JA, Pugliese A, Lernmark A; Swedish Childhood Study Group; Diabetes Incidence in Sweden Study Group; Type 1 Diabetes Component of the 13th International Histocompatibility Working Group. Valdes AM, et al. Among authors: kockum i. Diabetologia. 2005 Dec;48(12):2540-3. doi: 10.1007/s00125-005-0011-8. Epub 2005 Nov 18. Diabetologia. 2005. PMID: 16320082
Refining genetic associations in multiple sclerosis.
International Multiple Sclerosis Genetics Consortium (IMSGC). International Multiple Sclerosis Genetics Consortium (IMSGC). Lancet Neurol. 2008 Jul;7(7):567-9. doi: 10.1016/S1474-4422(08)70122-4. Lancet Neurol. 2008. PMID: 18565446 Free PMC article. No abstract available.
The non-inherited maternal HLA haplotype affects the risk for type 1 diabetes.
Akesson K, Carlsson A, Ivarsson SA, Johansson C, Weidby BM, Ludvigsson J, Gustavsson B, Lernmark A, Kockum I. Akesson K, et al. Among authors: kockum i. Int J Immunogenet. 2009 Feb;36(1):1-8. doi: 10.1111/j.1744-313X.2008.00802.x. Epub 2008 Nov 25. Int J Immunogenet. 2009. PMID: 19055605
Genetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis.
Ockinger J, Stridh P, Beyeen AD, Lundmark F, Seddighzadeh M, Oturai A, Sørensen PS, Lorentzen AR, Celius EG, Leppä V, Koivisto K, Tienari PJ, Alfredsson L, Padyukov L, Hillert J, Kockum I, Jagodic M, Olsson T. Ockinger J, et al. Among authors: kockum i. Genes Immun. 2010 Mar;11(2):142-54. doi: 10.1038/gene.2009.82. Epub 2009 Oct 29. Genes Immun. 2010. PMID: 19865101
A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis.
Mero IL, Lorentzen AR, Ban M, Smestad C, Celius EG, Aarseth JH, Myhr KM, Link J, Hillert J, Olsson T, Kockum I, Masterman T, Oturai AB, Søndergaard HB, Sellebjerg F, Saarela J, Kemppinen A, Elovaara I, Spurkland A, Dudbridge F, Lie BA, Harbo HF. Mero IL, et al. Among authors: kockum i. Eur J Hum Genet. 2010 Apr;18(4):502-4. doi: 10.1038/ejhg.2009.195. Epub 2009 Nov 4. Eur J Hum Genet. 2010. PMID: 19888296 Free PMC article.
HLA-DRB1 and month of birth in multiple sclerosis.
Ramagopalan SV, Link J, Byrnes JK, Dyment DA, Giovannoni G, Hintzen RQ, Sundqvist E, Kockum I, Smestad C, Lie BA, Harbo HF, Padyukov L, Alfredsson L, Olsson T, Sadovnick AD, Hillert J, Ebers GC. Ramagopalan SV, et al. Among authors: kockum i. Neurology. 2009 Dec 15;73(24):2107-11. doi: 10.1212/WNL.0b013e3181c679f3. Neurology. 2009. PMID: 20018638
313 results