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Urokinase-type plasminogen activator (uPA) is critical for progression of tuberous sclerosis complex 2 (TSC2)-deficient tumors.
Stepanova V, Dergilev KV, Holman KR, Parfyonova YV, Tsokolaeva ZI, Teter M, Atochina-Vasserman EN, Volgina A, Zaitsev SV, Lewis SP, Zabozlaev FG, Obraztsova K, Krymskaya VP, Cines DB. Stepanova V, et al. Among authors: holman kr. J Biol Chem. 2017 Dec 15;292(50):20528-20543. doi: 10.1074/jbc.M117.799593. Epub 2017 Sep 27. J Biol Chem. 2017. PMID: 28972182 Free PMC article.
Urokinase-type Plasminogen Activator (uPA) Promotes Angiogenesis by Attenuating Proline-rich Homeodomain Protein (PRH) Transcription Factor Activity and De-repressing Vascular Endothelial Growth Factor (VEGF) Receptor Expression.
Stepanova V, Jayaraman PS, Zaitsev SV, Lebedeva T, Bdeir K, Kershaw R, Holman KR, Parfyonova YV, Semina EV, Beloglazova IB, Tkachuk VA, Cines DB. Stepanova V, et al. Among authors: holman kr. J Biol Chem. 2016 Jul 15;291(29):15029-45. doi: 10.1074/jbc.M115.678490. Epub 2016 May 4. J Biol Chem. 2016. PMID: 27151212 Free PMC article.
Plugging the Leak: Empowering Women in Organic Chemistry.
Dibrell SE, Holman KR, Reisman SE. Dibrell SE, et al. Among authors: holman kr. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202111765. doi: 10.1002/anie.202111765. Epub 2021 Dec 20. Angew Chem Int Ed Engl. 2022. PMID: 34927782