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Urokinase-type plasminogen activator (uPA) is critical for progression of tuberous sclerosis complex 2 (TSC2)-deficient tumors.
J Biol Chem. 2017 Dec 15;292(50):20528-20543. doi: 10.1074/jbc.M117.799593. Epub 2017 Sep 27.
J Biol Chem. 2017.
PMID: 28972182
Free PMC article.
Urokinase-type Plasminogen Activator (uPA) Promotes Angiogenesis by Attenuating Proline-rich Homeodomain Protein (PRH) Transcription Factor Activity and De-repressing Vascular Endothelial Growth Factor (VEGF) Receptor Expression.
Stepanova V, Jayaraman PS, Zaitsev SV, Lebedeva T, Bdeir K, Kershaw R, Holman KR, Parfyonova YV, Semina EV, Beloglazova IB, Tkachuk VA, Cines DB.
Stepanova V, et al. Among authors: holman kr.
J Biol Chem. 2016 Jul 15;291(29):15029-45. doi: 10.1074/jbc.M115.678490. Epub 2016 May 4.
J Biol Chem. 2016.
PMID: 27151212
Free PMC article.
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Synthesis of Noraugustamine and Development of an Oxidative Heck/Aza-Wacker Cascade Cyclization.
Holman KR, Stanko AM, Richter MJR, Feng SS, Gessesse MN, Reisman SE.
Holman KR, et al.
Org Lett. 2022 Apr 29;24(16):3019-3023. doi: 10.1021/acs.orglett.2c00948. Epub 2022 Apr 15.
Org Lett. 2022.
PMID: 35426682
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Plugging the Leak: Empowering Women in Organic Chemistry.
Dibrell SE, Holman KR, Reisman SE.
Dibrell SE, et al. Among authors: holman kr.
Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202111765. doi: 10.1002/anie.202111765. Epub 2021 Dec 20.
Angew Chem Int Ed Engl. 2022.
PMID: 34927782
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Palladium-catalyzed cascade cyclizations involving C-C and C-X bond formation: strategic applications in natural product synthesis.
Holman KR , Stanko AM , Reisman SE .
Holman KR , et al.
Chem Soc Rev. 2021 Jul 21;50(14):7891-7908. doi: 10.1039/d0cs01385d. Epub 2021 May 26.
Chem Soc Rev. 2021.
PMID: 34037626
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