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Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity.
Dos Santos Fernandes GF, de Souza PC, Moreno-Viguri E, Santivañez-Veliz M, Paucar R, Pérez-Silanes S, Chegaev K, Guglielmo S, Lazzarato L, Fruttero R, Man Chin C, da Silva PB, Chorilli M, Solcia MC, Ribeiro CM, Silva CSP, Marino LB, Bosquesi PL, Hunt DM, de Carvalho LPS, de Souza Costa CA, Cho SH, Wang Y, Franzblau SG, Pavan FR, Dos Santos JL. Dos Santos Fernandes GF, et al. Among authors: lazzarato l. J Med Chem. 2017 Oct 26;60(20):8647-8660. doi: 10.1021/acs.jmedchem.7b01332. Epub 2017 Oct 16. J Med Chem. 2017. PMID: 28968083 Free PMC article.
Structure-Based Optimization of 1,2,4-Triazole-3-Thione Derivatives: Improving Inhibition of NDM-/VIM-Type Metallo-β-Lactamases and Synergistic Activity on Resistant Bacteria.
Bersani M, Failla M, Vascon F, Gianquinto E, Bertarini L, Baroni M, Cruciani G, Verdirosa F, Sannio F, Docquier JD, Cendron L, Spyrakis F, Lazzarato L, Tondi D. Bersani M, et al. Among authors: lazzarato l. Pharmaceuticals (Basel). 2023 Dec 2;16(12):1682. doi: 10.3390/ph16121682. Pharmaceuticals (Basel). 2023. PMID: 38139809 Free PMC article.
A new class of ibuprofen derivatives with reduced gastrotoxicity.
Lolli ML, Cena C, Medana C, Lazzarato L, Morini G, Coruzzi G, Manarini S, Fruttero R, Gasco A. Lolli ML, et al. Among authors: lazzarato l. J Med Chem. 2001 Oct 11;44(21):3463-8. doi: 10.1021/jm0108799. J Med Chem. 2001. PMID: 11585451
Amphiphilic NO-donor antioxidants.
Chegaev K, Lazzarato L, Rolando B, Marini E, Lopez GV, Bertinaria M, Di Stilo A, Fruttero R, Gasco A. Chegaev K, et al. Among authors: lazzarato l. ChemMedChem. 2007 Feb;2(2):234-40. doi: 10.1002/cmdc.200600248. ChemMedChem. 2007. PMID: 17183594
87 results