Gufford BT - Search Results

1

Variants in the CYP2B6 3'UTR Alter In Vitro and In Vivo CYP2B6 Activity: Potential Role of MicroRNAs.

Burgess KS, Ipe J, Swart M, Metzger IF, Lu J, Gufford BT, Thong N, Desta Z, Gaedigk R, Pearce RE, Gaedigk A, Liu Y, Skaar TC. Burgess KS, et al. Among authors: gufford bt. Clin Pharmacol Ther. 2018 Jul;104(1):130-138. doi: 10.1002/cpt.892. Epub 2017 Oct 25. Clin Pharmacol Ther. 2018. PMID: 28960269 Free PMC article.

2

Influence of Uridine Diphosphate Glucuronosyltransferase Family 1 Member A1 and Solute Carrier Organic Anion Transporter Family 1 Member B1 Polymorphisms and Efavirenz on Bilirubin Disposition in Healthy Volunteers.

Collins KS, Metzger IF, Gufford BT, Lu JB, Medeiros EB, Pratt VM, Skaar TC, Desta Z. Collins KS, et al. Among authors: gufford bt. Drug Metab Dispos. 2020 Mar;48(3):169-175. doi: 10.1124/dmd.119.089052. Epub 2019 Dec 30. Drug Metab Dispos. 2020. PMID: 31888882 Free PMC article. Clinical Trial.

3

Circulating miRNAs as Biomarkers for CYP2B6 Enzyme Activity.

Ipe J, Li R, Metzger IF, Bo Li Lu J, Gufford BT, Desta Z, Liu Y, Skaar TC. Ipe J, et al. Among authors: gufford bt. Clin Pharmacol Ther. 2021 Feb;109(2):485-493. doi: 10.1002/cpt.2018. Epub 2020 Oct 5. Clin Pharmacol Ther. 2021. PMID: 32772362 Free PMC article.

4

Chiral Plasma Pharmacokinetics and Urinary Excretion of Bupropion and Metabolites in Healthy Volunteers.

Masters AR, Gufford BT, Lu JB, Metzger IF, Jones DR, Desta Z. Masters AR, et al. Among authors: gufford bt. J Pharmacol Exp Ther. 2016 Aug;358(2):230-8. doi: 10.1124/jpet.116.232876. Epub 2016 Jun 2. J Pharmacol Exp Ther. 2016. PMID: 27255113 Free PMC article. Clinical Trial.

5

Inhibitory Effects of Probenecid on Pharmacokinetics of Tenofovir Disoproxil Fumarate and Emtricitabine for On-Demand HIV Preexposure Prophylaxis.

Liu SN, Gufford BT, Lu JBL, Bushman LR, Anderson PL, Bergstrom RF, Desta Z, Gupta SK. Liu SN, et al. Among authors: gufford bt. Clin Pharmacol Ther. 2020 May;107(5):1200-1208. doi: 10.1002/cpt.1714. Epub 2019 Dec 31. Clin Pharmacol Ther. 2020. PMID: 31675437 Free PMC article. Clinical Trial.

6

Influence of CYP2B6 Pharmacogenetics on Stereoselective Inhibition and Induction of Bupropion Metabolism by Efavirenz in Healthy Volunteers.

Gufford BT, Metzger IF, Bamfo NO, Benson EA, Masters AR, Lu JBL, Desta Z. Gufford BT, et al. J Pharmacol Exp Ther. 2022 Jul 7;382(3):313-26. doi: 10.1124/jpet.122.001277. Online ahead of print. J Pharmacol Exp Ther. 2022. PMID: 35798386 Free PMC article.

7

Stereoselective Glucuronidation of Bupropion Metabolites In Vitro and In Vivo.

Gufford BT, Lu JB, Metzger IF, Jones DR, Desta Z. Gufford BT, et al. Drug Metab Dispos. 2016 Apr;44(4):544-53. doi: 10.1124/dmd.115.068908. Epub 2016 Jan 22. Drug Metab Dispos. 2016. PMID: 26802129 Free PMC article. Clinical Trial.

8

Rifampin modulation of xeno- and endobiotic conjugating enzyme mRNA expression and associated microRNAs in human hepatocytes.

Gufford BT, Robarge JD, Eadon MT, Gao H, Lin H, Liu Y, Desta Z, Skaar TC. Gufford BT, et al. Pharmacol Res Perspect. 2018 Mar 26;6(2):e00386. doi: 10.1002/prp2.386. eCollection 2018 Apr. Pharmacol Res Perspect. 2018. PMID: 29610665 Free PMC article.

9

Implementation of a pharmacogenomics consult service to support the INGENIOUS trial.

Eadon MT, Desta Z, Levy KD, Decker BS, Pierson RC, Pratt VM, Callaghan JT, Rosenman MB, Carpenter JS, Holmes AM, McDonald CA, Benson EA, Patil AS, Vuppalanchi R, Gufford BT, Dave N, Robarge JD, Hyder MA, Haas DM, Kreutz RP, Dexter PR, Skaar TC, Flockhart DA. Eadon MT, et al. Among authors: gufford bt. Clin Pharmacol Ther. 2016 Jul;100(1):63-6. doi: 10.1002/cpt.347. Epub 2016 Mar 31. Clin Pharmacol Ther. 2016. PMID: 26850569 Free PMC article. Review.

10

Probenecid-Boosted Tenofovir: A Physiologically-Based Pharmacokinetic Model-Informed Strategy for On-Demand HIV Preexposure Prophylaxis.

Liu SN, Desta Z, Gufford BT. Liu SN, et al. Among authors: gufford bt. CPT Pharmacometrics Syst Pharmacol. 2020 Jan;9(1):40-47. doi: 10.1002/psp4.12481. Epub 2019 Dec 23. CPT Pharmacometrics Syst Pharmacol. 2020. PMID: 31749296 Free PMC article.

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