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Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication.
Kuss-Duerkop SK, Wang J, Mena I, White K, Metreveli G, Sakthivel R, Mata MA, Muñoz-Moreno R, Chen X, Krammer F, Diamond MS, Chen ZJ, García-Sastre A, Fontoura BMA. Kuss-Duerkop SK, et al. Among authors: wang j. PLoS Pathog. 2017 Sep 27;13(9):e1006635. doi: 10.1371/journal.ppat.1006635. eCollection 2017 Sep. PLoS Pathog. 2017. PMID: 28953980 Free PMC article.
Influenza Virus NS1 Protein-RNA Interactome Reveals Intron Targeting.
Zhang L, Wang J, Muñoz-Moreno R, Kim M, Sakthivel R, Mo W, Shao D, Anantharaman A, García-Sastre A, Conrad NK, Fontoura BMA. Zhang L, et al. Among authors: wang j. J Virol. 2018 Nov 27;92(24):e01634-18. doi: 10.1128/JVI.01634-18. Print 2018 Dec 15. J Virol. 2018. PMID: 30258002 Free PMC article.
Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression.
Zhang K, Shang G, Padavannil A, Wang J, Sakthivel R, Chen X, Kim M, Thompson MG, García-Sastre A, Lynch KW, Chen ZJ, Chook YM, Fontoura BMA. Zhang K, et al. Among authors: wang j. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12218-E12227. doi: 10.1073/pnas.1818012115. Epub 2018 Dec 11. Proc Natl Acad Sci U S A. 2018. PMID: 30538201 Free PMC article.
Structural basis for influenza virus NS1 protein block of mRNA nuclear export.
Zhang K, Xie Y, Muñoz-Moreno R, Wang J, Zhang L, Esparza M, García-Sastre A, Fontoura BMA, Ren Y. Zhang K, et al. Among authors: wang j. Nat Microbiol. 2019 Oct;4(10):1671-1679. doi: 10.1038/s41564-019-0482-x. Epub 2019 Jul 1. Nat Microbiol. 2019. PMID: 31263181 Free PMC article.
Chemical intervention of influenza virus mRNA nuclear export.
Esparza M, Mor A, Niederstrasser H, White K, White A, Zhang K, Gao S, Wang J, Liang J, Sho S, Sakthivel R, Sathe AA, Xing C, Muñoz-Moreno R, Shay JW, García-Sastre A, Ready J, Posner B, Fontoura BMA. Esparza M, et al. Among authors: wang j. PLoS Pathog. 2020 Apr 2;16(4):e1008407. doi: 10.1371/journal.ppat.1008407. eCollection 2020 Apr. PLoS Pathog. 2020. PMID: 32240278 Free PMC article.
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