Zacharias M - Search Results

1

Determinants of the assembly and function of antibody variable domains.

Herold EM, John C, Weber B, Kremser S, Eras J, Berner C, Deubler S, Zacharias M, Buchner J. Herold EM, et al. Among authors: zacharias m. Sci Rep. 2017 Sep 25;7(1):12276. doi: 10.1038/s41598-017-12519-9. Sci Rep. 2017. PMID: 28947772 Free PMC article.

2

Multiple molecular architectures of the eye lens chaperone αB-crystallin elucidated by a triple hybrid approach.

Braun N, Zacharias M, Peschek J, Kastenmüller A, Zou J, Hanzlik M, Haslbeck M, Rappsilber J, Buchner J, Weinkauf S. Braun N, et al. Among authors: zacharias m. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20491-6. doi: 10.1073/pnas.1111014108. Epub 2011 Dec 5. Proc Natl Acad Sci U S A. 2011. PMID: 22143763 Free PMC article.

3

A residue-specific shift in stability and amyloidogenicity of antibody variable domains.

Nokwe CN, Zacharias M, Yagi H, Hora M, Reif B, Goto Y, Buchner J. Nokwe CN, et al. Among authors: zacharias m. J Biol Chem. 2014 Sep 26;289(39):26829-26846. doi: 10.1074/jbc.M114.582247. Epub 2014 Aug 5. J Biol Chem. 2014. PMID: 25096580 Free PMC article.

4

The Antibody Light-Chain Linker Is Important for Domain Stability and Amyloid Formation.

Nokwe CN, Hora M, Zacharias M, Yagi H, John C, Reif B, Goto Y, Buchner J. Nokwe CN, et al. Among authors: zacharias m. J Mol Biol. 2015 Nov 6;427(22):3572-3586. doi: 10.1016/j.jmb.2015.09.012. Epub 2015 Sep 25. J Mol Biol. 2015. PMID: 26408269

5

Adenylylation of Tyr77 stabilizes Rab1b GTPase in an active state: A molecular dynamics simulation analysis.

Luitz MP, Bomblies R, Ramcke E, Itzen A, Zacharias M. Luitz MP, et al. Among authors: zacharias m. Sci Rep. 2016 Jan 28;6:19896. doi: 10.1038/srep19896. Sci Rep. 2016. PMID: 26818796 Free PMC article.

6

A Stable Mutant Predisposes Antibody Domains to Amyloid Formation through Specific Non-Native Interactions.

Nokwe CN, Hora M, Zacharias M, Yagi H, Peschek J, Reif B, Goto Y, Buchner J. Nokwe CN, et al. Among authors: zacharias m. J Mol Biol. 2016 Mar 27;428(6):1315-1332. doi: 10.1016/j.jmb.2016.01.015. Epub 2016 Jan 29. J Mol Biol. 2016. PMID: 26827727

7

A single residue switch reveals principles of antibody domain integrity.

Weber B, Brandl MJ, Pulido Cendales MD, Berner C, Pradhan T, Feind GM, Zacharias M, Reif B, Buchner J. Weber B, et al. Among authors: zacharias m. J Biol Chem. 2018 Nov 2;293(44):17107-17118. doi: 10.1074/jbc.RA118.005475. Epub 2018 Sep 18. J Biol Chem. 2018. PMID: 30228183 Free PMC article.

8

The structure and oxidation of the eye lens chaperone αA-crystallin.

Kaiser CJO, Peters C, Schmid PWN, Stavropoulou M, Zou J, Dahiya V, Mymrikov EV, Rockel B, Asami S, Haslbeck M, Rappsilber J, Reif B, Zacharias M, Buchner J, Weinkauf S. Kaiser CJO, et al. Among authors: zacharias m. Nat Struct Mol Biol. 2019 Dec;26(12):1141-1150. doi: 10.1038/s41594-019-0332-9. Epub 2019 Dec 2. Nat Struct Mol Biol. 2019. PMID: 31792453 Free PMC article.

9

Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation.

Kazman P, Vielberg MT, Pulido Cendales MD, Hunziger L, Weber B, Hegenbart U, Zacharias M, Köhler R, Schönland S, Groll M, Buchner J. Kazman P, et al. Among authors: zacharias m. Elife. 2020 Mar 10;9:e52300. doi: 10.7554/eLife.52300. Elife. 2020. PMID: 32151314 Free PMC article.

10

Molecular mechanism of amyloidogenic mutations in hypervariable regions of antibody light chains.

Rottenaicher GJ, Weber B, Rührnößl F, Kazman P, Absmeier RM, Hitzenberger M, Zacharias M, Buchner J. Rottenaicher GJ, et al. Among authors: zacharias m. J Biol Chem. 2021 Jan-Jun;296:100334. doi: 10.1016/j.jbc.2021.100334. Epub 2021 Jan 26. J Biol Chem. 2021. PMID: 33508322 Free PMC article.

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