Costales C - Search Results

1

In vitro studies with two human organic anion transporters: OAT2 and OAT7.

Mathialagan S, Costales C, Tylaska L, Kimoto E, Vildhede A, Johnson J, Johnson N, Sarashina T, Hashizume K, Isringhausen CD, Vermeer LMM, Wolff AR, Rodrigues AD. Mathialagan S, et al. Among authors: costales c. Xenobiotica. 2018 Oct;48(10):1037-1049. doi: 10.1080/00498254.2017.1384595. Epub 2017 Oct 13. Xenobiotica. 2018. PMID: 28945155

2

Reliable Rate Measurements for Active and Passive Hepatic Uptake Using Plated Human Hepatocytes.

Bi YA, Scialis RJ, Lazzaro S, Mathialagan S, Kimoto E, Keefer J, Zhang H, Vildhede AM, Costales C, Rodrigues AD, Tremaine LM, Varma MVS. Bi YA, et al. Among authors: costales c. AAPS J. 2017 May;19(3):787-796. doi: 10.1208/s12248-017-0051-2. Epub 2017 Feb 10. AAPS J. 2017. PMID: 28188574

3

Erratum to: Reliable Rate Measurements for Active and Passive Hepatic Uptake Using Plated Human Hepatocytes.

Bi YA, Scialis RJ, Lazzaro S, Mathialagan S, Kimoto E, Keefer J, Zhang H, Vildhede AM, Costales C, Rodrigues AD, Tremaine LM, Varma MVS. Bi YA, et al. Among authors: costales c. AAPS J. 2017 May;19(3):882. doi: 10.1208/s12248-017-0061-0. AAPS J. 2017. PMID: 28233243 No abstract available.

4

Organic Anion Transporter 2 Mediates Hepatic Uptake of Tolbutamide, a CYP2C9 Probe Drug.

Bi YA, Mathialagan S, Tylaska L, Fu M, Keefer J, Vildhede A, Costales C, Rodrigues AD, Varma MVS. Bi YA, et al. Among authors: costales c. J Pharmacol Exp Ther. 2018 Mar;364(3):390-398. doi: 10.1124/jpet.117.245951. Epub 2018 Jan 11. J Pharmacol Exp Ther. 2018. PMID: 29326367

5

Application of Physiologically Based Pharmacokinetic Modeling in Understanding Bosutinib Drug-Drug Interactions: Importance of Intestinal P-Glycoprotein.

Yamazaki S, Loi CM, Kimoto E, Costales C, Varma MV. Yamazaki S, et al. Among authors: costales c. Drug Metab Dispos. 2018 Aug;46(8):1200-1211. doi: 10.1124/dmd.118.080424. Epub 2018 May 8. Drug Metab Dispos. 2018. PMID: 29739809

6

Simultaneous Assessment of Transporter-Mediated Drug-Drug Interactions Using a Probe Drug Cocktail in Cynomolgus Monkey.

Kosa RE, Lazzaro S, Bi YA, Tierney B, Gates D, Modi S, Costales C, Rodrigues AD, Tremaine LM, Varma MV. Kosa RE, et al. Among authors: costales c. Drug Metab Dispos. 2018 Aug;46(8):1179-1189. doi: 10.1124/dmd.118.081794. Epub 2018 Jun 7. Drug Metab Dispos. 2018. PMID: 29880631

7

Quantitative Contribution of Six Major Transporters to the Hepatic Uptake of Drugs: "SLC-Phenotyping" Using Primary Human Hepatocytes.

Bi YA, Costales C, Mathialagan S, West M, Eatemadpour S, Lazzaro S, Tylaska L, Scialis R, Zhang H, Umland J, Kimoto E, Tess DA, Feng B, Tremaine LM, Varma MVS, Rodrigues AD. Bi YA, et al. Among authors: costales c. J Pharmacol Exp Ther. 2019 Jul;370(1):72-83. doi: 10.1124/jpet.119.257600. Epub 2019 Apr 11. J Pharmacol Exp Ther. 2019. PMID: 30975793

8

Physiologically-Based Pharmacokinetic Modeling Approach to Predict Rifampin-Mediated Intestinal P-Glycoprotein Induction.

Yamazaki S, Costales C, Lazzaro S, Eatemadpour S, Kimoto E, Varma MV. Yamazaki S, et al. Among authors: costales c. CPT Pharmacometrics Syst Pharmacol. 2019 Sep;8(9):634-642. doi: 10.1002/psp4.12458. Epub 2019 Sep 5. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 31420942 Free PMC article.

9

Nicotinic acid transport into human liver involves organic anion transporter 2 (SLC22A7).

Mathialagan S, Bi YA, Costales C, Kalgutkar AS, Rodrigues AD, Varma MVS. Mathialagan S, et al. Among authors: costales c. Biochem Pharmacol. 2020 Apr;174:113829. doi: 10.1016/j.bcp.2020.113829. Epub 2020 Jan 28. Biochem Pharmacol. 2020. PMID: 32001236

10

A Multiplexed HILIC-MS/HRMS Assay for the Assessment of Transporter Inhibition Biomarkers in Phase I Clinical Trials: Isobutyryl-Carnitine as an Organic Cation Transporter (OCT1) Biomarker.

Luo L, Ramanathan R, Horlbogen L, Mathialagan S, Costales C, Vourvahis M, Holliman CL, Rodrigues AD. Luo L, et al. Among authors: costales c. Anal Chem. 2020 Jul 21;92(14):9745-9754. doi: 10.1021/acs.analchem.0c01144. Epub 2020 Jul 2. Anal Chem. 2020. PMID: 32551505

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