Örfi L - Search Results

1

Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma.

Brägelmann J, Dammert MA, Dietlein F, Heuckmann JM, Choidas A, Böhm S, Richters A, Basu D, Tischler V, Lorenz C, Habenberger P, Fang Z, Ortiz-Cuaran S, Leenders F, Eickhoff J, Koch U, Getlik M, Termathe M, Sallouh M, Greff Z, Varga Z, Balke-Want H, French CA, Peifer M, Reinhardt HC, Örfi L, Kéri G, Ansén S, Heukamp LC, Büttner R, Rauh D, Klebl BM, Thomas RK, Sos ML. Brägelmann J, et al. Among authors: orfi l. Cell Rep. 2017 Sep 19;20(12):2833-2845. doi: 10.1016/j.celrep.2017.08.082. Cell Rep. 2017. PMID: 28930680 Free PMC article.

2

Relationship between lipophilicity and antitumor activity of molecule library of Mannich ketones determined by high-performance liquid chromatography, clogP calculation and cytotoxicity test.

Hollósy F, Lóránd T, Orfi L, Erös D, Kéri G, Idei M. Hollósy F, et al. Among authors: orfi l. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Mar 5;768(2):361-8. doi: 10.1016/s1570-0232(02)00004-1. J Chromatogr B Analyt Technol Biomed Life Sci. 2002. PMID: 11888064

3

Interaction of tyrosine kinase inhibitors with the human multidrug transporter proteins, MDR1 and MRP1.

Hegedus T, Orfi L, Seprodi A, Váradi A, Sarkadi B, Kéri G. Hegedus T, et al. Among authors: orfi l. Biochim Biophys Acta. 2002 Jul 18;1587(2-3):318-25. doi: 10.1016/s0925-4439(02)00095-9. Biochim Biophys Acta. 2002. PMID: 12084474 Free article. Review.

4

Validation subset selections for extrapolation oriented QSPAR models.

Szántai-Kis C, Kövesdi I, Kéri G, Orfi L. Szántai-Kis C, et al. Among authors: orfi l. Mol Divers. 2003;7(1):37-43. doi: 10.1023/b:modi.0000006538.99122.00. Mol Divers. 2003. PMID: 14768902

5

High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter.

Ozvegy-Laczka C, Hegedus T, Várady G, Ujhelly O, Schuetz JD, Váradi A, Kéri G, Orfi L, Német K, Sarkadi B. Ozvegy-Laczka C, et al. Among authors: orfi l. Mol Pharmacol. 2004 Jun;65(6):1485-95. doi: 10.1124/mol.65.6.1485. Mol Pharmacol. 2004. PMID: 15155841

6

Characterization of a conserved structural determinant controlling protein kinase sensitivity to selective inhibitors.

Blencke S, Zech B, Engkvist O, Greff Z, Orfi L, Horváth Z, Kéri G, Ullrich A, Daub H. Blencke S, et al. Among authors: orfi l. Chem Biol. 2004 May;11(5):691-701. doi: 10.1016/j.chembiol.2004.02.029. Chem Biol. 2004. PMID: 15157880

7

Improved, high yield synthesis of 3H-quinazolin-4-ones, the key intermediates of recently developed drugs.

Orfi L, Wáczek F, Pató J, Varga I, Hegymegi-Barakonyi B, Houghten RA, Kéri G. Orfi L, et al. Curr Med Chem. 2004 Oct;11(19):2549-53. doi: 10.2174/0929867043364423. Curr Med Chem. 2004. PMID: 15544462

8

Acid-base profiling of imatinib (gleevec) and its fragments.

Szakács Z, Béni S, Varga Z, Orfi L, Kéri G, Noszál B. Szakács Z, et al. Among authors: orfi l. J Med Chem. 2005 Jan 13;48(1):249-55. doi: 10.1021/jm049546c. J Med Chem. 2005. PMID: 15634018

9

Comparison of ELISA-based tyrosine kinase assays for screening EGFR inhibitors.

Varkondi E, Schäfer E, Bökönyi G, Gyökeres T, Orfi L, Petak I, Pap A, Szokoloczi O, Keri G, Schwab R. Varkondi E, et al. Among authors: orfi l. J Recept Signal Transduct Res. 2005;25(1):45-56. doi: 10.1081/rrs-200055095. J Recept Signal Transduct Res. 2005. PMID: 15960394

10

Proteomic characterization of the angiogenesis inhibitor SU6668 reveals multiple impacts on cellular kinase signaling.

Godl K, Gruss OJ, Eickhoff J, Wissing J, Blencke S, Weber M, Degen H, Brehmer D, Orfi L, Horváth Z, Kéri G, Müller S, Cotten M, Ullrich A, Daub H. Godl K, et al. Among authors: orfi l. Cancer Res. 2005 Aug 1;65(15):6919-26. doi: 10.1158/0008-5472.CAN-05-0574. Cancer Res. 2005. PMID: 16061676 Free article.

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