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DMTS is an effective treatment in both inhalation and injection models for cyanide poisoning using unanesthetized mice.
Clin Toxicol (Phila). 2018 May;56(5):332-341. doi: 10.1080/15563650.2017.1376749. Epub 2017 Sep 19.
Clin Toxicol (Phila). 2018.
PMID: 28922956
Free PMC article.
A novel aqueous dimethyl trisulfide formulation is effective at low doses against cyanide toxicity in non-anesthetized mice and rats.
Lippner DS, Hildenberger DM, Rhoomes MO, Winborn JN, Dixon H, McDonough J, Rockwood GA.
Lippner DS, et al. Among authors: rhoomes mo.
Clin Toxicol (Phila). 2022 Jan;60(1):83-94. doi: 10.1080/15563650.2021.1935991. Epub 2021 Jul 5.
Clin Toxicol (Phila). 2022.
PMID: 34219566
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Cyanide Poisoning Compromises Gene Pathways Modulating Cardiac Injury in Vivo.
Ma KH, Lippner DS, Basi KA, DeLeon SM, Cappuccio WR, Rhoomes MO, Hildenberger DM, Hoard-Fruchey HM, Rockwood GA.
Ma KH, et al. Among authors: rhoomes mo.
Chem Res Toxicol. 2021 Jun 21;34(6):1530-1541. doi: 10.1021/acs.chemrestox.0c00467. Epub 2021 Apr 29.
Chem Res Toxicol. 2021.
PMID: 33914522
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Evaluation of aqueous dimethyl trisulfide as an antidote to a highly lethal cyanide poisoning in a large swine model.
Hendry-Hofer TB, Severance CC, Bhadra S, Ng PC, Soules K, Lippner DS, Hildenberger DM, Rhoomes MO, Winborn JN, Logue BA, Rockwood GA, Bebarta VS.
Hendry-Hofer TB, et al. Among authors: rhoomes mo.
Clin Toxicol (Phila). 2022 Jan;60(1):95-101. doi: 10.1080/15563650.2021.1935992. Epub 2021 Jun 18.
Clin Toxicol (Phila). 2022.
PMID: 34142637
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