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A DNA vaccine for Crimean-Congo hemorrhagic fever protects against disease and death in two lethal mouse models.
Garrison AR, Shoemaker CJ, Golden JW, Fitzpatrick CJ, Suschak JJ, Richards MJ, Badger CV, Six CM, Martin JD, Hannaman D, Zivcec M, Bergeron E, Koehler JW, Schmaljohn CS. Garrison AR, et al. Among authors: hannaman d. PLoS Negl Trop Dis. 2017 Sep 18;11(9):e0005908. doi: 10.1371/journal.pntd.0005908. eCollection 2017 Sep. PLoS Negl Trop Dis. 2017. PMID: 28922426 Free PMC article.
A DNA vaccine for venezuelan equine encephalitis virus delivered by intramuscular electroporation elicits high levels of neutralizing antibodies in multiple animal models and provides protective immunity to mice and nonhuman primates.
Dupuy LC, Richards MJ, Ellefsen B, Chau L, Luxembourg A, Hannaman D, Livingston BD, Schmaljohn CS. Dupuy LC, et al. Among authors: hannaman d. Clin Vaccine Immunol. 2011 May;18(5):707-16. doi: 10.1128/CVI.00030-11. Epub 2011 Mar 30. Clin Vaccine Immunol. 2011. PMID: 21450977 Free PMC article.
A Phase 1 clinical trial of Hantaan virus and Puumala virus M-segment DNA vaccines for haemorrhagic fever with renal syndrome delivered by intramuscular electroporation.
Hooper JW, Moon JE, Paolino KM, Newcomer R, McLain DE, Josleyn M, Hannaman D, Schmaljohn C. Hooper JW, et al. Among authors: hannaman d. Clin Microbiol Infect. 2014 May;20 Suppl 5:110-7. doi: 10.1111/1469-0691.12553. Epub 2014 Mar 7. Clin Microbiol Infect. 2014. PMID: 24447183 Free article. Clinical Trial.
Codon-optimized filovirus DNA vaccines delivered by intramuscular electroporation protect cynomolgus macaques from lethal Ebola and Marburg virus challenges.
Grant-Klein RJ, Altamura LA, Badger CV, Bounds CE, Van Deusen NM, Kwilas SA, Vu HA, Warfield KL, Hooper JW, Hannaman D, Dupuy LC, Schmaljohn CS. Grant-Klein RJ, et al. Among authors: hannaman d. Hum Vaccin Immunother. 2015;11(8):1991-2004. doi: 10.1080/21645515.2015.1039757. Hum Vaccin Immunother. 2015. PMID: 25996997 Free PMC article. Clinical Trial.
Human Polyclonal Antibodies Produced through DNA Vaccination of Transchromosomal Cattle Provide Mice with Post-Exposure Protection against Lethal Zaire and Sudan Ebolaviruses.
Bounds CE, Kwilas SA, Kuehne AI, Brannan JM, Bakken RR, Dye JM, Hooper JW, Dupuy LC, Ellefsen B, Hannaman D, Wu H, Jiao JA, Sullivan EJ, Schmaljohn CS. Bounds CE, et al. Among authors: hannaman d. PLoS One. 2015 Sep 30;10(9):e0137786. doi: 10.1371/journal.pone.0137786. eCollection 2015. PLoS One. 2015. PMID: 26422247 Free PMC article.
An immunoinformatics-derived DNA vaccine encoding human class II T cell epitopes of Ebola virus, Sudan virus, and Venezuelan equine encephalitis virus is immunogenic in HLA transgenic mice.
Bounds CE, Terry FE, Moise L, Hannaman D, Martin WD, De Groot AS, Suschak JJ, Dupuy LC, Schmaljohn CS. Bounds CE, et al. Among authors: hannaman d. Hum Vaccin Immunother. 2017 Dec 2;13(12):2824-2836. doi: 10.1080/21645515.2017.1329788. Epub 2017 Jun 2. Hum Vaccin Immunother. 2017. PMID: 28575582 Free PMC article.
A Multiagent Alphavirus DNA Vaccine Delivered by Intramuscular Electroporation Elicits Robust and Durable Virus-Specific Immune Responses in Mice and Rabbits and Completely Protects Mice against Lethal Venezuelan, Western, and Eastern Equine Encephalitis Virus Aerosol Challenges.
Dupuy LC, Richards MJ, Livingston BD, Hannaman D, Schmaljohn CS. Dupuy LC, et al. Among authors: hannaman d. J Immunol Res. 2018 Jun 3;2018:8521060. doi: 10.1155/2018/8521060. eCollection 2018. J Immunol Res. 2018. PMID: 29967804 Free PMC article.
A Phase 2a Randomized, Double-Blind, Dose-Optimizing Study to Evaluate the Immunogenicity and Safety of a Bivalent DNA Vaccine for Hemorrhagic Fever with Renal Syndrome Delivered by Intramuscular Electroporation.
Hooper J, Paolino KM, Mills K, Kwilas S, Josleyn M, Cohen M, Somerville B, Wisniewski M, Norris S, Hill B, Sanchez-Lockhart M, Hannaman D, Schmaljohn CS. Hooper J, et al. Among authors: hannaman d. Vaccines (Basel). 2020 Jul 11;8(3):377. doi: 10.3390/vaccines8030377. Vaccines (Basel). 2020. PMID: 32664486 Free PMC article.
68 results